Physical activity in older cancer patients: evidence and clinical implications

This mini-review examines the role of physical activity in older cancer patients based on current evidence. As cancer incidence increases with age, older patients face unique challenges including comorbidities and functional decline. This review synthesizes findings regarding physical activity’s imp...

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Main Authors: Shugo Yajima, Shin Kobayashi, Tadayoshi Hashimoto, Hitoshi Masuda
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1613268/full
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author Shugo Yajima
Shugo Yajima
Shin Kobayashi
Tadayoshi Hashimoto
Hitoshi Masuda
author_facet Shugo Yajima
Shugo Yajima
Shin Kobayashi
Tadayoshi Hashimoto
Hitoshi Masuda
author_sort Shugo Yajima
collection DOAJ
description This mini-review examines the role of physical activity in older cancer patients based on current evidence. As cancer incidence increases with age, older patients face unique challenges including comorbidities and functional decline. This review synthesizes findings regarding physical activity’s impact on cancer prevention, post-operative recovery, and long-term outcomes in older adults. Evidence consistently demonstrates that moderate physical activity reduces risk for several cancers, improves post-surgical recovery, and enhances quality of life while potentially improving survival in cancer survivors. We also address the independent risks of sedentary behavior and briefly discuss alternative forms of physical activity such as yoga and tai chi that may be suitable for older adults. While optimal exercise regimens for specific populations remain under investigation, this review provides evidence-based guidance for incorporating physical activity across the cancer care continuum, emphasizing approaches that account for age-related considerations and functional status of older adults.
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institution Kabale University
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publishDate 2025-08-01
publisher Frontiers Media S.A.
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series Frontiers in Oncology
spelling doaj-art-9534475d20554718afa0641563500ddd2025-08-20T04:02:51ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-08-011510.3389/fonc.2025.16132681613268Physical activity in older cancer patients: evidence and clinical implicationsShugo Yajima0Shugo Yajima1Shin Kobayashi2Tadayoshi Hashimoto3Hitoshi Masuda4Department of Urology, National Cancer Center Hospital East, Kashiwa, JapanPerioperative Treatment Development Promotion Office, National Cancer Center Hospital East, Kashiwa, JapanPerioperative Treatment Development Promotion Office, National Cancer Center Hospital East, Kashiwa, JapanPerioperative Treatment Development Promotion Office, National Cancer Center Hospital East, Kashiwa, JapanDepartment of Urology, National Cancer Center Hospital East, Kashiwa, JapanThis mini-review examines the role of physical activity in older cancer patients based on current evidence. As cancer incidence increases with age, older patients face unique challenges including comorbidities and functional decline. This review synthesizes findings regarding physical activity’s impact on cancer prevention, post-operative recovery, and long-term outcomes in older adults. Evidence consistently demonstrates that moderate physical activity reduces risk for several cancers, improves post-surgical recovery, and enhances quality of life while potentially improving survival in cancer survivors. We also address the independent risks of sedentary behavior and briefly discuss alternative forms of physical activity such as yoga and tai chi that may be suitable for older adults. While optimal exercise regimens for specific populations remain under investigation, this review provides evidence-based guidance for incorporating physical activity across the cancer care continuum, emphasizing approaches that account for age-related considerations and functional status of older adults.https://www.frontiersin.org/articles/10.3389/fonc.2025.1613268/fullcancerelderlyexercisesurvivorshipcancer preventionrehabilitation
spellingShingle Shugo Yajima
Shugo Yajima
Shin Kobayashi
Tadayoshi Hashimoto
Hitoshi Masuda
Physical activity in older cancer patients: evidence and clinical implications
Frontiers in Oncology
cancer
elderly
exercise
survivorship
cancer prevention
rehabilitation
title Physical activity in older cancer patients: evidence and clinical implications
title_full Physical activity in older cancer patients: evidence and clinical implications
title_fullStr Physical activity in older cancer patients: evidence and clinical implications
title_full_unstemmed Physical activity in older cancer patients: evidence and clinical implications
title_short Physical activity in older cancer patients: evidence and clinical implications
title_sort physical activity in older cancer patients evidence and clinical implications
topic cancer
elderly
exercise
survivorship
cancer prevention
rehabilitation
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1613268/full
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