Effect of Succinate-Containing Infusion Solution
on Cellular Structures in Children in the Perioperative Period

Objective: to evaluate the effect of a 1.5% crystalloid polyionic Reamberin solution on cellular structures in children in the perioperative period. Subjects and methods. A randomized prospective study was conducted in 117 children aged 1 to 18 years during different surgical interventions under ane...

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Main Authors: V. V. Lazarev, K. R. Ermolaeva, V. S. Kochkin, L. E. Tsypin, T. G. Popova, D. V. Nikolaev, A. A. Bologov, N. N. Vaganov
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2015-02-01
Series:Общая реаниматология
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Online Access:https://www.reanimatology.com/rmt/article/view/1444
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author V. V. Lazarev
K. R. Ermolaeva
V. S. Kochkin
L. E. Tsypin
T. G. Popova
D. V. Nikolaev
A. A. Bologov
N. N. Vaganov
author_facet V. V. Lazarev
K. R. Ermolaeva
V. S. Kochkin
L. E. Tsypin
T. G. Popova
D. V. Nikolaev
A. A. Bologov
N. N. Vaganov
author_sort V. V. Lazarev
collection DOAJ
description Objective: to evaluate the effect of a 1.5% crystalloid polyionic Reamberin solution on cellular structures in children in the perioperative period. Subjects and methods. A randomized prospective study was conducted in 117 children aged 1 to 18 years during different surgical interventions under anesthesia with sevoflurane, fentanyl, or rocuronium to provide ASA I—II estimates. A study group included 55 children, in whom basic infusion therapy was switched to infusions of 1.5% Reamberin solution 20 minutes before the end of a surgical intervention. A comparison group comprised 62 children, in whom basic infusion therapy was switched to infusions of 0.9% NaCl solution 20 minutes before the end of surgery. In the study and control groups, the solutions were administered in a dose of 6—10 ml/kg depending on age at a rate of 2 ml/min. Results. 1.5% Reamberin solution was found to contribute to earlier and significant improvement in the function of cellular structures in children in the perioperative period.
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publishDate 2015-02-01
publisher Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
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spelling doaj-art-952eaae50db847278c09f84e611c9de52025-08-20T02:59:35ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102015-02-01111333810.15360/1813-9779-2015-1-33-381436Effect of Succinate-Containing Infusion Solution
on Cellular Structures in Children in the Perioperative PeriodV. V. Lazarev0K. R. Ermolaeva1V. S. Kochkin2L. E. Tsypin3T. G. Popova4D. V. Nikolaev5A. A. Bologov6N. N. Vaganov7N.I. Pirogov Russian National Research Medical University, Ministry of Health, Moscow, Russia 1, Ostrovityanov St., Moscow 117997N.I. Pirogov Russian National Research Medical University, Ministry of Health, Moscow, Russia 1, Ostrovityanov St., Moscow 117997Republican Children's Clinical Hospital, Ministry of Health, Moscow, Russia 117, Leninsky Prospect, Moscow 117997N.I. Pirogov Russian National Research Medical University, Ministry of Health, Moscow, Russia 1, Ostrovityanov St., Moscow 117997N.I. Pirogov Russian National Research Medical University, Ministry of Health, Moscow, Russia 1, Ostrovityanov St., Moscow 117997Medas Research and Technical Center, Moscow, Russia 12, Chistoprudnyi Boulevard, Moscow 101000Republican Children's Clinical Hospital, Ministry of Health, Moscow, Russia 117, Leninsky Prospect, Moscow 117997Republican Children's Clinical Hospital, Ministry of Health, Moscow, Russia 117, Leninsky Prospect, Moscow 117997Objective: to evaluate the effect of a 1.5% crystalloid polyionic Reamberin solution on cellular structures in children in the perioperative period. Subjects and methods. A randomized prospective study was conducted in 117 children aged 1 to 18 years during different surgical interventions under anesthesia with sevoflurane, fentanyl, or rocuronium to provide ASA I—II estimates. A study group included 55 children, in whom basic infusion therapy was switched to infusions of 1.5% Reamberin solution 20 minutes before the end of a surgical intervention. A comparison group comprised 62 children, in whom basic infusion therapy was switched to infusions of 0.9% NaCl solution 20 minutes before the end of surgery. In the study and control groups, the solutions were administered in a dose of 6—10 ml/kg depending on age at a rate of 2 ml/min. Results. 1.5% Reamberin solution was found to contribute to earlier and significant improvement in the function of cellular structures in children in the perioperative period.https://www.reanimatology.com/rmt/article/view/1444infusion therapycellular structuresphase anglesuccinate-containing solutionchildren
spellingShingle V. V. Lazarev
K. R. Ermolaeva
V. S. Kochkin
L. E. Tsypin
T. G. Popova
D. V. Nikolaev
A. A. Bologov
N. N. Vaganov
Effect of Succinate-Containing Infusion Solution
on Cellular Structures in Children in the Perioperative Period
Общая реаниматология
infusion therapy
cellular structures
phase angle
succinate-containing solution
children
title Effect of Succinate-Containing Infusion Solution
on Cellular Structures in Children in the Perioperative Period
title_full Effect of Succinate-Containing Infusion Solution
on Cellular Structures in Children in the Perioperative Period
title_fullStr Effect of Succinate-Containing Infusion Solution
on Cellular Structures in Children in the Perioperative Period
title_full_unstemmed Effect of Succinate-Containing Infusion Solution
on Cellular Structures in Children in the Perioperative Period
title_short Effect of Succinate-Containing Infusion Solution
on Cellular Structures in Children in the Perioperative Period
title_sort effect of succinate containing infusion solution
on cellular structures in children in the perioperative period
topic infusion therapy
cellular structures
phase angle
succinate-containing solution
children
url https://www.reanimatology.com/rmt/article/view/1444
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AT letsypin effectofsuccinatecontaininginfusionsolutiononcellularstructuresinchildrenintheperioperativeperiod
AT tgpopova effectofsuccinatecontaininginfusionsolutiononcellularstructuresinchildrenintheperioperativeperiod
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