Automation of Hessian-Based Tubularity Measure Response Function in 3D Biomedical Images

The blood vessels and nerve trees consist of tubular objects interconnected into a complex tree- or web-like structure that has a range of structural scale 5 μm diameter capillaries to 3 cm aorta. This large-scale range presents two major problems; one is just making the measurements, and the other...

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Main Authors: Oleksandr P. Dzyubak, Erik L. Ritman
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2011/920401
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author Oleksandr P. Dzyubak
Erik L. Ritman
author_facet Oleksandr P. Dzyubak
Erik L. Ritman
author_sort Oleksandr P. Dzyubak
collection DOAJ
description The blood vessels and nerve trees consist of tubular objects interconnected into a complex tree- or web-like structure that has a range of structural scale 5 μm diameter capillaries to 3 cm aorta. This large-scale range presents two major problems; one is just making the measurements, and the other is the exponential increase of component numbers with decreasing scale. With the remarkable increase in the volume imaged by, and resolution of, modern day 3D imagers, it is almost impossible to make manual tracking of the complex multiscale parameters from those large image data sets. In addition, the manual tracking is quite subjective and unreliable. We propose a solution for automation of an adaptive nonsupervised system for tracking tubular objects based on multiscale framework and use of Hessian-based object shape detector incorporating National Library of Medicine Insight Segmentation and Registration Toolkit (ITK) image processing libraries.
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institution Kabale University
issn 1687-4188
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language English
publishDate 2011-01-01
publisher Wiley
record_format Article
series International Journal of Biomedical Imaging
spelling doaj-art-95261801f1994942884b445f729c468d2025-02-03T05:46:56ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962011-01-01201110.1155/2011/920401920401Automation of Hessian-Based Tubularity Measure Response Function in 3D Biomedical ImagesOleksandr P. Dzyubak0Erik L. Ritman1Physiological Imaging Research Laboratory, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USAPhysiological Imaging Research Laboratory, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USAThe blood vessels and nerve trees consist of tubular objects interconnected into a complex tree- or web-like structure that has a range of structural scale 5 μm diameter capillaries to 3 cm aorta. This large-scale range presents two major problems; one is just making the measurements, and the other is the exponential increase of component numbers with decreasing scale. With the remarkable increase in the volume imaged by, and resolution of, modern day 3D imagers, it is almost impossible to make manual tracking of the complex multiscale parameters from those large image data sets. In addition, the manual tracking is quite subjective and unreliable. We propose a solution for automation of an adaptive nonsupervised system for tracking tubular objects based on multiscale framework and use of Hessian-based object shape detector incorporating National Library of Medicine Insight Segmentation and Registration Toolkit (ITK) image processing libraries.http://dx.doi.org/10.1155/2011/920401
spellingShingle Oleksandr P. Dzyubak
Erik L. Ritman
Automation of Hessian-Based Tubularity Measure Response Function in 3D Biomedical Images
International Journal of Biomedical Imaging
title Automation of Hessian-Based Tubularity Measure Response Function in 3D Biomedical Images
title_full Automation of Hessian-Based Tubularity Measure Response Function in 3D Biomedical Images
title_fullStr Automation of Hessian-Based Tubularity Measure Response Function in 3D Biomedical Images
title_full_unstemmed Automation of Hessian-Based Tubularity Measure Response Function in 3D Biomedical Images
title_short Automation of Hessian-Based Tubularity Measure Response Function in 3D Biomedical Images
title_sort automation of hessian based tubularity measure response function in 3d biomedical images
url http://dx.doi.org/10.1155/2011/920401
work_keys_str_mv AT oleksandrpdzyubak automationofhessianbasedtubularitymeasureresponsefunctionin3dbiomedicalimages
AT eriklritman automationofhessianbasedtubularitymeasureresponsefunctionin3dbiomedicalimages