Malnutrition in orthopaedic trauma outcomes (MOTO): orthopedic trauma patients can be effectively screened and stratified for risk of malnutrition using prealbumin. A preliminary outcome study

Abstract. Objectives:. To evaluate prealbumin (PAB) as a prognostic indicator for early detection of malnutrition risk upon admission and its correlation with in-hospital complications and length of stay (LOS) in patients with orthopedic trauma. Methods:. Design:. Retrospective cohort. Setting:. Urb...

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Main Authors: Anna Jacques, DO, Timothy Niedzielak, DO, Samuel G. Eaddy, DO, Radleigh Santos, PhD, Stacey L. Tannenbaum, PhD, RDN, Joel Rush, DO, Emily Keener, DO, William Neway, III, DO, Bradley Roth, DO, Edward Perez, MD, Brian J. Cross, DO
Format: Article
Language:English
Published: Wolters Kluwer 2025-06-01
Series:OTA International
Online Access:http://journals.lww.com/10.1097/OI9.0000000000000402
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Summary:Abstract. Objectives:. To evaluate prealbumin (PAB) as a prognostic indicator for early detection of malnutrition risk upon admission and its correlation with in-hospital complications and length of stay (LOS) in patients with orthopedic trauma. Methods:. Design:. Retrospective cohort. Setting:. Urban academic Level 1 trauma center. Patients/Participants:. One hundred fifty-eight patients aged 18 years or older with acute traumatic fractures indicated for primary surgical fixation between 2019 and 2022 were included. Serum laboratory tests consisting of PAB, C-reactive protein, complete blood counts, and complete metabolic panel were obtained within 24 hours of arrival. Outcome Measures and Comparisons:. Primary outcome measures included characterization of patient risk factors for increased intensive care unit LOS, hospital LOS, and in-hospital complications. Secondary outcome measures included characterization of patients who were stratified as “at risk” for malnutrition by PAB < 20 mg/dL and identification of complication predictors. Results:. Fifty-one (32%) patients were stratified as “at risk” for malnutrition based on serum PAB < 20 mg/dL drawn within 24 hours of arrival. These patients had longer median hospital LOS (P < 0.001), were more likely to stay in the hospital longer than 7 days (P < 0.009) and >14 days (OR = 3.20, 95% CI 1.17–9.07, P < 0.001), and had twice the amount of postoperative complications during their hospital stay (P = 0.04) than patients with PAB ≥ 20 mg/dL. Conclusions:. Patients with orthopaedic trauma can reliably and cost-effectively be screened and stratified for risk of malnutrition using PAB drawn with immediate admission labs. Level of Evidence:. Level III.
ISSN:2574-2167