Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones

Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones

A chitosan-supported CuI (CS@CuI) catalyst was developed for the synthesis of quinazolinones from 2-halobenzoic acids (including iodine and bromine) and amidines. The reaction proceeds under mild reaction conditions, demonstrating a broad substrate scope (30 examples) and good catalytic efficiency (...

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Bibliographic Details
Main Authors: Xuhong Zhao, Weishuang Li, Mengli Yang, Bojie Li, Yaoyao Zhang, Lizhen Huang, Lei Zhu
Format: Article
Language:English
Published: Beilstein-Institut 2025-04-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
chitosan-supported cui catalyst
cyclization reaction
mild conditions
quinazolinone
Online Access:https://doi.org/10.3762/bjoc.21.67
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