Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones
A chitosan-supported CuI (CS@CuI) catalyst was developed for the synthesis of quinazolinones from 2-halobenzoic acids (including iodine and bromine) and amidines. The reaction proceeds under mild reaction conditions, demonstrating a broad substrate scope (30 examples) and good catalytic efficiency (...
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| Format: | Article |
| Language: | English |
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Beilstein-Institut
2025-04-01
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| Series: | Beilstein Journal of Organic Chemistry |
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| Online Access: | https://doi.org/10.3762/bjoc.21.67 |
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| _version_ | 1850204864672432128 |
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| author | Xuhong Zhao Weishuang Li Mengli Yang Bojie Li Yaoyao Zhang Lizhen Huang Lei Zhu |
| author_facet | Xuhong Zhao Weishuang Li Mengli Yang Bojie Li Yaoyao Zhang Lizhen Huang Lei Zhu |
| author_sort | Xuhong Zhao |
| collection | DOAJ |
| description | A chitosan-supported CuI (CS@CuI) catalyst was developed for the synthesis of quinazolinones from 2-halobenzoic acids (including iodine and bromine) and amidines. The reaction proceeds under mild reaction conditions, demonstrating a broad substrate scope (30 examples) and good catalytic efficiency (up to 99% yield). |
| format | Article |
| id | doaj-art-951903d609964eef9fdcc45d0146f897 |
| institution | OA Journals |
| issn | 1860-5397 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj-art-951903d609964eef9fdcc45d0146f8972025-08-20T02:11:12ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972025-04-0121183984410.3762/bjoc.21.671860-5397-21-67Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinonesXuhong Zhao0Weishuang Li1Mengli Yang2Bojie Li3Yaoyao Zhang4Lizhen Huang5Lei Zhu6School of Chemistry and Materials Science, Hubei Provincial Engineering Research Center of Key Technologies in Modern Paper and Hygiene Products Manufacturing, Hubei Engineering University, Xiaogan 432000, China School of Chemistry and Materials Science, Hubei Provincial Engineering Research Center of Key Technologies in Modern Paper and Hygiene Products Manufacturing, Hubei Engineering University, Xiaogan 432000, China School of Chemistry and Materials Science, Hubei Provincial Engineering Research Center of Key Technologies in Modern Paper and Hygiene Products Manufacturing, Hubei Engineering University, Xiaogan 432000, China School of Chemistry and Materials Science, Hubei Provincial Engineering Research Center of Key Technologies in Modern Paper and Hygiene Products Manufacturing, Hubei Engineering University, Xiaogan 432000, China School of Chemistry and Materials Science, Hubei Provincial Engineering Research Center of Key Technologies in Modern Paper and Hygiene Products Manufacturing, Hubei Engineering University, Xiaogan 432000, China School of Chemistry and Materials Science, Hubei Provincial Engineering Research Center of Key Technologies in Modern Paper and Hygiene Products Manufacturing, Hubei Engineering University, Xiaogan 432000, China School of Chemistry and Materials Science, Hubei Provincial Engineering Research Center of Key Technologies in Modern Paper and Hygiene Products Manufacturing, Hubei Engineering University, Xiaogan 432000, China A chitosan-supported CuI (CS@CuI) catalyst was developed for the synthesis of quinazolinones from 2-halobenzoic acids (including iodine and bromine) and amidines. The reaction proceeds under mild reaction conditions, demonstrating a broad substrate scope (30 examples) and good catalytic efficiency (up to 99% yield).https://doi.org/10.3762/bjoc.21.67chitosan-supported cui catalystcyclization reactionmild conditionsquinazolinone |
| spellingShingle | Xuhong Zhao Weishuang Li Mengli Yang Bojie Li Yaoyao Zhang Lizhen Huang Lei Zhu Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones Beilstein Journal of Organic Chemistry chitosan-supported cui catalyst cyclization reaction mild conditions quinazolinone |
| title | Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones |
| title_full | Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones |
| title_fullStr | Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones |
| title_full_unstemmed | Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones |
| title_short | Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones |
| title_sort | chitosan supported cui catalyzed cascade reaction of 2 halobenzoic acids and amidines for the synthesis of quinazolinones |
| topic | chitosan-supported cui catalyst cyclization reaction mild conditions quinazolinone |
| url | https://doi.org/10.3762/bjoc.21.67 |
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