Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones
A chitosan-supported CuI (CS@CuI) catalyst was developed for the synthesis of quinazolinones from 2-halobenzoic acids (including iodine and bromine) and amidines. The reaction proceeds under mild reaction conditions, demonstrating a broad substrate scope (30 examples) and good catalytic efficiency (...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Beilstein-Institut
2025-04-01
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| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.21.67 |
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| Summary: | A chitosan-supported CuI (CS@CuI) catalyst was developed for the synthesis of quinazolinones from 2-halobenzoic acids (including iodine and bromine) and amidines. The reaction proceeds under mild reaction conditions, demonstrating a broad substrate scope (30 examples) and good catalytic efficiency (up to 99% yield). |
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| ISSN: | 1860-5397 |