A novel anxiety-associated SNP identified in LYNX2 (LYPD1) is associated with decreased protein binding to nicotinic acetylcholine receptors

A novel anxiety-associated SNP identified in LYNX2 (LYPD1) is associated with decreased protein binding to nicotinic acetylcholine receptors

IntroductionAnxiety disorders are among the most common mental illnesses in the US. An estimated 31.1% of U.S. adults experience any anxiety disorder at some time in their lives. Understanding some of the molecular underpinnings of anxiety could lead to improved treatments over current strategies fo...

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Main Authors: Kristin R. Anderson, Wenpeng Cao, Hui Sun Lee, Mark A. Crenshaw, Talulla B. Palumbo, Ethan Fisher-Perez, Amanda DeGraaf, Peter Rogu, Maria A. Beatty, Gabrielle M. Gracias, Avani V. Pisapati, Katie Hoffman, Krystle J. McLaughlin, Almut Hupbach, Wonpil Im, X. Frank Zhang, Julie M. Miwa
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Lynx2
LYPD1
nicotinic acetylcholine receptors
anxiety disorders
human psychology
human DNA analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2024.1347543/full
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