Management and Treatment of Hepatitis B Virus in Patients with Hiv Infection: A Practical Guide for Health Care Professionals

The management and treatment of HIV and hepatitis B virus (HBV)-coinfected patients present specific challenges for clinicians. The morbidity and mortality related to these concomitant infections are growing concerns, while the use of antiviral drugs effective against both viruses complicates therap...

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Main Authors: Marina B. Klein, Jean-Guy Baril, Marc-André Charron, Claude Fortin, Richard Lalonde, Marie-France Matte, Marc Poliquin, Annie Talbot, Rachel Therrien, Cécile Tremblay, Benoît Trottier, Irina Tsarevsky, Jean-Pierre Villeneuve
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2011/686918
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author Marina B. Klein
Jean-Guy Baril
Marc-André Charron
Claude Fortin
Richard Lalonde
Marie-France Matte
Marc Poliquin
Annie Talbot
Rachel Therrien
Cécile Tremblay
Benoît Trottier
Irina Tsarevsky
Jean-Pierre Villeneuve
author_facet Marina B. Klein
Jean-Guy Baril
Marc-André Charron
Claude Fortin
Richard Lalonde
Marie-France Matte
Marc Poliquin
Annie Talbot
Rachel Therrien
Cécile Tremblay
Benoît Trottier
Irina Tsarevsky
Jean-Pierre Villeneuve
author_sort Marina B. Klein
collection DOAJ
description The management and treatment of HIV and hepatitis B virus (HBV)-coinfected patients present specific challenges for clinicians. The morbidity and mortality related to these concomitant infections are growing concerns, while the use of antiviral drugs effective against both viruses complicates therapeutic decision making. The present document provides guidelines for physicians regarding care and treatment of patients coinfected with HIV and HBV. Primary prevention of HBV in HIV-positive patients is achieved through appropriate vaccination schedules. Follow-up before treatment of HBV may include liver biopsy, screening for hepatocellular carcinoma and testing for esophageal varicies in cases of cirrhosis. In HBV-infected patients requiring treatment, recommendations regarding initiation, duration and choice of first-line drugs are made. Finally, in the case of resistance, appropriate alternative therapies are necessary.
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language English
publishDate 2011-01-01
publisher Wiley
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series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-95040b0703c24e119fbc94c4cbd92dca2025-08-20T03:37:02ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322011-01-01223889610.1155/2011/686918Management and Treatment of Hepatitis B Virus in Patients with Hiv Infection: A Practical Guide for Health Care ProfessionalsMarina B. Klein0Jean-Guy Baril1Marc-André Charron2Claude Fortin3Richard Lalonde4Marie-France Matte5Marc Poliquin6Annie Talbot7Rachel Therrien8Cécile Tremblay9Benoît Trottier10Irina Tsarevsky11Jean-Pierre Villeneuve12Division of Infectious Diseases and Immunodeficiency Service, McGill University Health Centre, Montréal, Québec, CanadaClinique médicale du Quartier Latin, Montréal, Québec, CanadaClinique médicale du Quartier Latin, Montréal, Québec, CanadaUnité hospitalière de recherche, d’enseignement et de soins sur le sida, Centre hospitalier de l’Université de Montréal, Hôpital Notre-Dame, CanadaDivision of Infectious Diseases and Immunodeficiency Service, McGill University Health Centre, Montréal, Québec, CanadaProgramme National de Mentorat sur le VIH-Sida, CanadaUnité hospitalière de recherche, d’enseignement et de soins sur le sida, Centre hospitalier de l’Université de Montréal, Hôpital Notre-Dame, CanadaClinique médicale du Quartier Latin, Montréal, Québec, CanadaUnité hospitalière de recherche, d’enseignement et de soins sur le sida, Centre hospitalier de l’Université de Montréal, Hôpital Hôtel-Dieu de Montréal, Montréal, Québec, CanadaUnité hospitalière de recherche, d’enseignement et de soins sur le sida, Centre hospitalier de l’Université de Montréal, Hôpital Hôtel-Dieu de Montréal, Montréal, Québec, CanadaUnité hospitalière de recherche, d’enseignement et de soins sur le sida, Centre hospitalier de l’Université de Montréal, Hôpital Saint-Luc, CanadaService de lutte contre les infections transmissibles sexuellement et par le sang, ministère de la Santé et des Services sociaux, CanadaCentre hospitalier de l’Université de Montréal, Hôpital Saint-Luc, Montréal, Québec, CanadaThe management and treatment of HIV and hepatitis B virus (HBV)-coinfected patients present specific challenges for clinicians. The morbidity and mortality related to these concomitant infections are growing concerns, while the use of antiviral drugs effective against both viruses complicates therapeutic decision making. The present document provides guidelines for physicians regarding care and treatment of patients coinfected with HIV and HBV. Primary prevention of HBV in HIV-positive patients is achieved through appropriate vaccination schedules. Follow-up before treatment of HBV may include liver biopsy, screening for hepatocellular carcinoma and testing for esophageal varicies in cases of cirrhosis. In HBV-infected patients requiring treatment, recommendations regarding initiation, duration and choice of first-line drugs are made. Finally, in the case of resistance, appropriate alternative therapies are necessary.http://dx.doi.org/10.1155/2011/686918
spellingShingle Marina B. Klein
Jean-Guy Baril
Marc-André Charron
Claude Fortin
Richard Lalonde
Marie-France Matte
Marc Poliquin
Annie Talbot
Rachel Therrien
Cécile Tremblay
Benoît Trottier
Irina Tsarevsky
Jean-Pierre Villeneuve
Management and Treatment of Hepatitis B Virus in Patients with Hiv Infection: A Practical Guide for Health Care Professionals
Canadian Journal of Infectious Diseases and Medical Microbiology
title Management and Treatment of Hepatitis B Virus in Patients with Hiv Infection: A Practical Guide for Health Care Professionals
title_full Management and Treatment of Hepatitis B Virus in Patients with Hiv Infection: A Practical Guide for Health Care Professionals
title_fullStr Management and Treatment of Hepatitis B Virus in Patients with Hiv Infection: A Practical Guide for Health Care Professionals
title_full_unstemmed Management and Treatment of Hepatitis B Virus in Patients with Hiv Infection: A Practical Guide for Health Care Professionals
title_short Management and Treatment of Hepatitis B Virus in Patients with Hiv Infection: A Practical Guide for Health Care Professionals
title_sort management and treatment of hepatitis b virus in patients with hiv infection a practical guide for health care professionals
url http://dx.doi.org/10.1155/2011/686918
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