Synthesis, Analytical Characterization, and Human CB<sub>1</sub> Receptor Binding Studies of the Chloroindole Analogues of the Synthetic Cannabinoid MDMB-CHMICA

Synthesis, Analytical Characterization, and Human CB<sub>1</sub> Receptor Binding Studies of the Chloroindole Analogues of the Synthetic Cannabinoid MDMB-CHMICA

Synthetic cannabinoids (SCs) are one of the largest groups of new psychoactive substances (NPSs). However, the relationship between their chemical structure and the affinity to human CB<sub>1</sub> receptors (hCB<sub>1</sub>), which mediates their psychotropic activity, is no...

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Bibliographic Details
Main Authors: Sascha Münster-Müller, Steven Hansen, Tobias Lucas, Arianna Giorgetti, Lukas Mogler, Svenja Fischmann, Folker Westphal, Volker Auwärter, Michael Pütz, Till Opatz
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
new psychoactive substances (NPSs)
MDMB-CHMICA
cannabimimetics
analytical characterization
pharmacological evaluation
Online Access:https://www.mdpi.com/2218-273X/14/11/1414
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