Limbitis Secondary to Autologous Serum Eye Drops in a Patient with Atopic Keratoconjunctivitis
Purpose. Report a case of limbitis secondary to autologous serum eye drops in a patient with atopic keratoconjunctivitis. Design. Interventional case report. Methods. A 32-year-old African American female with atopic keratoconjunctivitis (AKC) presented with chronic dry eye and diffuse punctate epit...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/576521 |
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| author | Jeffrey David Welder Pejman Bakhtiari Ali R. Djalilian |
| author_facet | Jeffrey David Welder Pejman Bakhtiari Ali R. Djalilian |
| author_sort | Jeffrey David Welder |
| collection | DOAJ |
| description | Purpose. Report a case of limbitis secondary to autologous serum eye drops in a patient with atopic keratoconjunctivitis. Design. Interventional case report. Methods. A 32-year-old African American female with atopic keratoconjunctivitis (AKC) presented with chronic dry eye and diffuse punctate epithelial erosions refractory to conservative treatment. She was initially managed with cyclosporine ophthalmic 0.05% in addition to preservative-free artificial tears and olopatadine hydrochloride 0.2% for 6 months. She was later placed on autologous serum eye drops (ASEDs) and 4 weeks into treatment developed unilateral limbitis. The limbitis resolved shortly after stopping ASEDs in that eye; however, the drops were continued in the contralateral eye, which subsequently developed limbitis within 2 weeks. ASEDs were discontinued in both eyes, and the patient has remained quiet ever since. Results. Patient with a history of AKC and no prior history of limbitis developed limbitis shortly after starting ASEDs, which resolved promptly after discontinuation of therapy with no subsequent recurrence of inflammation. Conclusion. ASEDs are widely used in the treatment of complicated or treatment refractory dry eye. The potential side effects should be kept in mind when prescribing ASEDs for any patient, especially in those with underlying immunological diseases and circulating inflammatory factors. |
| format | Article |
| id | doaj-art-9501e4c34b7f45db99835fa4417cb989 |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-9501e4c34b7f45db99835fa4417cb9892025-02-03T05:58:15ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302011-01-01201110.1155/2011/576521576521Limbitis Secondary to Autologous Serum Eye Drops in a Patient with Atopic KeratoconjunctivitisJeffrey David Welder0Pejman Bakhtiari1Ali R. Djalilian2Illinois Eye and Ear Infirmary, University of Illinois at Chicago, 1855 West Taylor Street, Chicago, IL 60612, USAIllinois Eye and Ear Infirmary, University of Illinois at Chicago, 1855 West Taylor Street, Chicago, IL 60612, USAIllinois Eye and Ear Infirmary, University of Illinois at Chicago, 1855 West Taylor Street, Chicago, IL 60612, USAPurpose. Report a case of limbitis secondary to autologous serum eye drops in a patient with atopic keratoconjunctivitis. Design. Interventional case report. Methods. A 32-year-old African American female with atopic keratoconjunctivitis (AKC) presented with chronic dry eye and diffuse punctate epithelial erosions refractory to conservative treatment. She was initially managed with cyclosporine ophthalmic 0.05% in addition to preservative-free artificial tears and olopatadine hydrochloride 0.2% for 6 months. She was later placed on autologous serum eye drops (ASEDs) and 4 weeks into treatment developed unilateral limbitis. The limbitis resolved shortly after stopping ASEDs in that eye; however, the drops were continued in the contralateral eye, which subsequently developed limbitis within 2 weeks. ASEDs were discontinued in both eyes, and the patient has remained quiet ever since. Results. Patient with a history of AKC and no prior history of limbitis developed limbitis shortly after starting ASEDs, which resolved promptly after discontinuation of therapy with no subsequent recurrence of inflammation. Conclusion. ASEDs are widely used in the treatment of complicated or treatment refractory dry eye. The potential side effects should be kept in mind when prescribing ASEDs for any patient, especially in those with underlying immunological diseases and circulating inflammatory factors.http://dx.doi.org/10.1155/2011/576521 |
| spellingShingle | Jeffrey David Welder Pejman Bakhtiari Ali R. Djalilian Limbitis Secondary to Autologous Serum Eye Drops in a Patient with Atopic Keratoconjunctivitis Case Reports in Ophthalmological Medicine |
| title | Limbitis Secondary to Autologous Serum Eye Drops in a Patient with Atopic Keratoconjunctivitis |
| title_full | Limbitis Secondary to Autologous Serum Eye Drops in a Patient with Atopic Keratoconjunctivitis |
| title_fullStr | Limbitis Secondary to Autologous Serum Eye Drops in a Patient with Atopic Keratoconjunctivitis |
| title_full_unstemmed | Limbitis Secondary to Autologous Serum Eye Drops in a Patient with Atopic Keratoconjunctivitis |
| title_short | Limbitis Secondary to Autologous Serum Eye Drops in a Patient with Atopic Keratoconjunctivitis |
| title_sort | limbitis secondary to autologous serum eye drops in a patient with atopic keratoconjunctivitis |
| url | http://dx.doi.org/10.1155/2011/576521 |
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