Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insights
Mortality and morbidity from cardiovascular diseases are common worldwide. In order to improve survival and quality of life for this patient population, extensive efforts are being made to establish effective therapeutic modalities. New treatment options are needed, it seems. In addition to treating...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-12-01
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| Series: | Frontiers in Cell and Developmental Biology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2024.1472103/full |
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| author | Zahra Sadat Razavi Simin Farokhi Golnaz Mahmoudvand Arian Karimi-Rouzbahani Bahareh Farasati-Far Samaneh Tahmasebi-Ghorabi Hamidreza Pazoki-Toroudi Masoud Saadat-Fakhr Hamed Afkhami Hamed Afkhami Hamed Afkhami |
| author_facet | Zahra Sadat Razavi Simin Farokhi Golnaz Mahmoudvand Arian Karimi-Rouzbahani Bahareh Farasati-Far Samaneh Tahmasebi-Ghorabi Hamidreza Pazoki-Toroudi Masoud Saadat-Fakhr Hamed Afkhami Hamed Afkhami Hamed Afkhami |
| author_sort | Zahra Sadat Razavi |
| collection | DOAJ |
| description | Mortality and morbidity from cardiovascular diseases are common worldwide. In order to improve survival and quality of life for this patient population, extensive efforts are being made to establish effective therapeutic modalities. New treatment options are needed, it seems. In addition to treating cardiovascular diseases, cell therapy is one of the most promising medical platforms. One of the most effective therapeutic approaches in this area is stem cell therapy. In stem cell biology, multipotent stem cells and pluripotent stem cells are divided into two types. There is evidence that stem cell therapy could be used as a therapeutic approach for cardiovascular diseases based on multiple lines of evidence. The effectiveness of stem cell therapies in humans has been studied in several clinical trials. In spite of the challenges associated with stem cell therapy, it appears that resolving them may lead to stem cells being used in cardiovascular disease patients. This may be an effective therapeutic approach. By mounting these stem cells on biological scaffolds, their effect can be enhanced. |
| format | Article |
| id | doaj-art-94fdf4e94add444394e9e2bb343b3c40 |
| institution | OA Journals |
| issn | 2296-634X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj-art-94fdf4e94add444394e9e2bb343b3c402025-08-20T02:34:20ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2024-12-011210.3389/fcell.2024.14721031472103Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insightsZahra Sadat Razavi0Simin Farokhi1Golnaz Mahmoudvand2Arian Karimi-Rouzbahani3Bahareh Farasati-Far4Samaneh Tahmasebi-Ghorabi5Hamidreza Pazoki-Toroudi6Masoud Saadat-Fakhr7Hamed Afkhami8Hamed Afkhami9Hamed Afkhami10Physiology Research Center, Iran University of Medical Sciences, Tehran, IranStudent Research Committee, USERN Office, Lorestan University of Medical Sciences, Khorramabad, IranStudent Research Committee, USERN Office, Lorestan University of Medical Sciences, Khorramabad, IranStudent Research Committee, USERN Office, Lorestan University of Medical Sciences, Khorramabad, IranDepartment of Chemistry, Iran University of Science and Technology, Tehran, IranMaster of Health Education, Research Expert, Clinical Research Development Unit, Emam Khomeini Hospital, Ilam University of Medical Sciences, Ilam, IranPhysiology Research Center, Iran University of Medical Sciences, Tehran, IranFaculty of Medicine, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, IranCellular and Molecular Research Center, Qom University of Medical Sciences, Qom, IranNervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, IranDepartment of Medical Microbiology, Faculty of Medicine, Shahed University, Tehran, IranMortality and morbidity from cardiovascular diseases are common worldwide. In order to improve survival and quality of life for this patient population, extensive efforts are being made to establish effective therapeutic modalities. New treatment options are needed, it seems. In addition to treating cardiovascular diseases, cell therapy is one of the most promising medical platforms. One of the most effective therapeutic approaches in this area is stem cell therapy. In stem cell biology, multipotent stem cells and pluripotent stem cells are divided into two types. There is evidence that stem cell therapy could be used as a therapeutic approach for cardiovascular diseases based on multiple lines of evidence. The effectiveness of stem cell therapies in humans has been studied in several clinical trials. In spite of the challenges associated with stem cell therapy, it appears that resolving them may lead to stem cells being used in cardiovascular disease patients. This may be an effective therapeutic approach. By mounting these stem cells on biological scaffolds, their effect can be enhanced.https://www.frontiersin.org/articles/10.3389/fcell.2024.1472103/fullcardiovascular heart diseaseheart failurestem cellcell therapybio scaffold |
| spellingShingle | Zahra Sadat Razavi Simin Farokhi Golnaz Mahmoudvand Arian Karimi-Rouzbahani Bahareh Farasati-Far Samaneh Tahmasebi-Ghorabi Hamidreza Pazoki-Toroudi Masoud Saadat-Fakhr Hamed Afkhami Hamed Afkhami Hamed Afkhami Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insights Frontiers in Cell and Developmental Biology cardiovascular heart disease heart failure stem cell cell therapy bio scaffold |
| title | Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insights |
| title_full | Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insights |
| title_fullStr | Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insights |
| title_full_unstemmed | Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insights |
| title_short | Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insights |
| title_sort | stem cells and bio scaffolds for the treatment of cardiovascular diseases new insights |
| topic | cardiovascular heart disease heart failure stem cell cell therapy bio scaffold |
| url | https://www.frontiersin.org/articles/10.3389/fcell.2024.1472103/full |
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