Orientia tsutsugamushi in human scrub typhus eschars shows tropism for dendritic cells and monocytes rather than endothelium.

Orientia tsutsugamushi in human scrub typhus eschars shows tropism for dendritic cells and monocytes rather than endothelium.

Scrub typhus is a common and underdiagnosed cause of febrile illness in Southeast Asia, caused by infection with Orientia tsutsugamushi. Inoculation of the organism at a cutaneous mite bite site commonly results in formation of a localized pathological skin reaction termed an eschar. The site of dev...

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Main Authors: Daniel H Paris, Rattanaphone Phetsouvanh, Ampai Tanganuchitcharnchai, Margaret Jones, Kemajittra Jenjaroen, Manivanh Vongsouvath, David P J Ferguson, Stuart D Blacksell, Paul N Newton, Nicholas P J Day, Gareth D H Turner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0001466&type=printable
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