Punicic Acid: A Potential Nutraceutical Compound in Pomegranate Seed Oil and Its Cardiovascular Benefits

Pomegranate seed oil (PSO) is rich in punicic acid (PA), a conjugated isomer of α-linolenic acid, and exhibits a range of pharmacological properties. Given the significant role of nutraceuticals in the prevention of various diseases, PA stands out as an important phytoconstituent within this categor...

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Main Authors: Manal Almoraie, Jeremy Spencer, Carol Wagstaff
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/14/14/2412
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author Manal Almoraie
Jeremy Spencer
Carol Wagstaff
author_facet Manal Almoraie
Jeremy Spencer
Carol Wagstaff
author_sort Manal Almoraie
collection DOAJ
description Pomegranate seed oil (PSO) is rich in punicic acid (PA), a conjugated isomer of α-linolenic acid, and exhibits a range of pharmacological properties. Given the significant role of nutraceuticals in the prevention of various diseases, PA stands out as an important phytoconstituent within this category. This review aimed to examine the composition of PSOs and their positive effects on cardiovascular risk factors. PA possesses potent antioxidant and anti-inflammatory effects, as well as aids in managing obesity and diabetes while improving lipid profiles. Additionally, the diverse cardiovascular health benefits associated with PSO consumption are detailed. There are various health benefits that are derived from PSO consumption; however, despite these promising findings, there remains a critical need for further clinical studies to validate these effects.
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series Foods
spelling doaj-art-94f42e78693c4ee79db120732e25b67c2025-08-20T03:32:32ZengMDPI AGFoods2304-81582025-07-011414241210.3390/foods14142412Punicic Acid: A Potential Nutraceutical Compound in Pomegranate Seed Oil and Its Cardiovascular BenefitsManal Almoraie0Jeremy Spencer1Carol Wagstaff2Department of Food and Nutritional Sciences, University of Reading, Whiteknights, Reading RG6 6DZ, UKDepartment of Food and Nutritional Sciences, University of Reading, Whiteknights, Reading RG6 6DZ, UKDepartment of Food and Nutritional Sciences, University of Reading, Whiteknights, Reading RG6 6DZ, UKPomegranate seed oil (PSO) is rich in punicic acid (PA), a conjugated isomer of α-linolenic acid, and exhibits a range of pharmacological properties. Given the significant role of nutraceuticals in the prevention of various diseases, PA stands out as an important phytoconstituent within this category. This review aimed to examine the composition of PSOs and their positive effects on cardiovascular risk factors. PA possesses potent antioxidant and anti-inflammatory effects, as well as aids in managing obesity and diabetes while improving lipid profiles. Additionally, the diverse cardiovascular health benefits associated with PSO consumption are detailed. There are various health benefits that are derived from PSO consumption; however, despite these promising findings, there remains a critical need for further clinical studies to validate these effects.https://www.mdpi.com/2304-8158/14/14/2412pomegranate seed oilpunicic acidpharmacologicalconsumptionnutraceutical
spellingShingle Manal Almoraie
Jeremy Spencer
Carol Wagstaff
Punicic Acid: A Potential Nutraceutical Compound in Pomegranate Seed Oil and Its Cardiovascular Benefits
Foods
pomegranate seed oil
punicic acid
pharmacological
consumption
nutraceutical
title Punicic Acid: A Potential Nutraceutical Compound in Pomegranate Seed Oil and Its Cardiovascular Benefits
title_full Punicic Acid: A Potential Nutraceutical Compound in Pomegranate Seed Oil and Its Cardiovascular Benefits
title_fullStr Punicic Acid: A Potential Nutraceutical Compound in Pomegranate Seed Oil and Its Cardiovascular Benefits
title_full_unstemmed Punicic Acid: A Potential Nutraceutical Compound in Pomegranate Seed Oil and Its Cardiovascular Benefits
title_short Punicic Acid: A Potential Nutraceutical Compound in Pomegranate Seed Oil and Its Cardiovascular Benefits
title_sort punicic acid a potential nutraceutical compound in pomegranate seed oil and its cardiovascular benefits
topic pomegranate seed oil
punicic acid
pharmacological
consumption
nutraceutical
url https://www.mdpi.com/2304-8158/14/14/2412
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AT carolwagstaff punicicacidapotentialnutraceuticalcompoundinpomegranateseedoilanditscardiovascularbenefits