GC–MS analysis and in silico approaches to Stichopus hermanii as anti-inflammatory through PKC-β inhibition

GC–MS analysis and in silico approaches to Stichopus hermanii as anti-inflammatory through PKC-β inhibition

Targeting the NF-κB signaling pathway is an interesting approach for anti-inflammatory therapy. Inhibition of the PKC-β pathway has shown to reducing NF-κB activity. In silico studies using molecular docking techniques used to determine the potentialof Stichopus hermanii as an anti-inflammatory agen...

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Bibliographic Details
Main Authors: Kurnia Fatwati, Asmawati Amin, Lenni Indriani, Rusdina Bte Ladju, Fuad Husain Akbar, Nurlindah Hamrun
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Results in Chemistry
Subjects:
Anti-inflammatory agents
Drug development
Molecular docking simulation
PKC-β inhibition
ADME-Tox
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625000694
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