The effect of hypervigilance on visual working memory in insomnia disorder: Evidence from ERP study
Background: This study investigates the impact of hypervigilance on visual working memory in individuals with insomnia disorder using event-related potentials (ERP) and time-frequency analysis. Methods: A total of 45 insomnia disorder (ID) patients and 43 healthy controls (HC) participated in a visu...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-10-01
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| Series: | Brain Research Bulletin |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0361923025003156 |
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| author | Chao Yang Junhua Mei Xinhua Song Jinzhen Jiang Cancheng Li Anan Ping Xingke Wang Shaodi Wang Sheng Yang Yingchao Jiang Kun Wang Yushan Bian Yan Wang Guohua Chen Changming Wang Xiaoli Li |
| author_facet | Chao Yang Junhua Mei Xinhua Song Jinzhen Jiang Cancheng Li Anan Ping Xingke Wang Shaodi Wang Sheng Yang Yingchao Jiang Kun Wang Yushan Bian Yan Wang Guohua Chen Changming Wang Xiaoli Li |
| author_sort | Chao Yang |
| collection | DOAJ |
| description | Background: This study investigates the impact of hypervigilance on visual working memory in individuals with insomnia disorder using event-related potentials (ERP) and time-frequency analysis. Methods: A total of 45 insomnia disorder (ID) patients and 43 healthy controls (HC) participated in a visual working memory task that involved encoding, maintaining, and retrieving visual stimuli (S1 and S2) of blurred and clear pictures. ERP components and frequency bands were analyzed across these stages. Results: The ID group had significantly altered ERP amplitudes and increased theta and beta activity across all stages compared to the HC group, indicating hypervigilance and cognitive resource consumption during working memory processing. In the encoding stage, P100 and N170 amplitudes were significantly correlated with insomnia severity (ISI), while P200 amplitude was linked to HAMA score. During the maintenance stage, CNV amplitude and increased theta power were associated with sustained attention, which correlated with ISI scores, reflecting the burden of maintaining attention in hypervigilance states. In the retrieval stage, the ID group showed reduced P300 amplitudes but increased LPC amplitudes, highlighting their struggle with memory updating and complex cognitive processing under hypervigilance states. Conclusion: These findings suggest that ID patients exhibit hypervigilance, which affects the efficiency of visual working memory, impairs attention regulation, and increases cognitive load during tasks. Understanding these mechanisms may provide insights for clinical interventions aimed at improving cognitive function in ID patients. |
| format | Article |
| id | doaj-art-94e15e1a16fd45aa8aa2ec41bbb3b5d8 |
| institution | Kabale University |
| issn | 1873-2747 |
| language | English |
| publishDate | 2025-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brain Research Bulletin |
| spelling | doaj-art-94e15e1a16fd45aa8aa2ec41bbb3b5d82025-08-20T03:41:52ZengElsevierBrain Research Bulletin1873-27472025-10-0123011150310.1016/j.brainresbull.2025.111503The effect of hypervigilance on visual working memory in insomnia disorder: Evidence from ERP studyChao Yang0Junhua Mei1Xinhua Song2Jinzhen Jiang3Cancheng Li4Anan Ping5Xingke Wang6Shaodi Wang7Sheng Yang8Yingchao Jiang9Kun Wang10Yushan Bian11Yan Wang12Guohua Chen13Changming Wang14Xiaoli Li15State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern, Beijing Normal University, Beijing, ChinaDepartment of Neurology, Wuhan First Hospital, Wuhan, ChinaDepartment of Neurology, Wuhan First Hospital, Wuhan, China; Clinical College of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, ChinaDepartment of encephalopathy, Jinhua Traditional Chinese Medicine Hospital, Jinhua, ChinaSchool of Biological Science and Medical Engineering, Beihang University, Beijing, ChinaState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern, Beijing Normal University, Beijing, ChinaState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern, Beijing Normal University, Beijing, ChinaState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern, Beijing Normal University, Beijing, ChinaState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern, Beijing Normal University, Beijing, ChinaCollege of Psychology and Mental Health, North China University of Science and Technology, Tangshan, ChinaCollege of Psychology and Mental Health, North China University of Science and Technology, Tangshan, ChinaCollege of Psychology and Mental Health, North China University of Science and Technology, Tangshan, ChinaCollege of Psychology and Mental Health, North China University of Science and Technology, Tangshan, ChinaDepartment of Neurology, Wuhan First Hospital, Wuhan, China; Clinical College of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, National Center for Neurological Disorders, Beijing, China; Corresponding authors.State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern, Beijing Normal University, Beijing, China; Corresponding authors.Background: This study investigates the impact of hypervigilance on visual working memory in individuals with insomnia disorder using event-related potentials (ERP) and time-frequency analysis. Methods: A total of 45 insomnia disorder (ID) patients and 43 healthy controls (HC) participated in a visual working memory task that involved encoding, maintaining, and retrieving visual stimuli (S1 and S2) of blurred and clear pictures. ERP components and frequency bands were analyzed across these stages. Results: The ID group had significantly altered ERP amplitudes and increased theta and beta activity across all stages compared to the HC group, indicating hypervigilance and cognitive resource consumption during working memory processing. In the encoding stage, P100 and N170 amplitudes were significantly correlated with insomnia severity (ISI), while P200 amplitude was linked to HAMA score. During the maintenance stage, CNV amplitude and increased theta power were associated with sustained attention, which correlated with ISI scores, reflecting the burden of maintaining attention in hypervigilance states. In the retrieval stage, the ID group showed reduced P300 amplitudes but increased LPC amplitudes, highlighting their struggle with memory updating and complex cognitive processing under hypervigilance states. Conclusion: These findings suggest that ID patients exhibit hypervigilance, which affects the efficiency of visual working memory, impairs attention regulation, and increases cognitive load during tasks. Understanding these mechanisms may provide insights for clinical interventions aimed at improving cognitive function in ID patients.http://www.sciencedirect.com/science/article/pii/S0361923025003156Insomnia disorderVisual working memoryEvent-related potentialsHypervigilance |
| spellingShingle | Chao Yang Junhua Mei Xinhua Song Jinzhen Jiang Cancheng Li Anan Ping Xingke Wang Shaodi Wang Sheng Yang Yingchao Jiang Kun Wang Yushan Bian Yan Wang Guohua Chen Changming Wang Xiaoli Li The effect of hypervigilance on visual working memory in insomnia disorder: Evidence from ERP study Brain Research Bulletin Insomnia disorder Visual working memory Event-related potentials Hypervigilance |
| title | The effect of hypervigilance on visual working memory in insomnia disorder: Evidence from ERP study |
| title_full | The effect of hypervigilance on visual working memory in insomnia disorder: Evidence from ERP study |
| title_fullStr | The effect of hypervigilance on visual working memory in insomnia disorder: Evidence from ERP study |
| title_full_unstemmed | The effect of hypervigilance on visual working memory in insomnia disorder: Evidence from ERP study |
| title_short | The effect of hypervigilance on visual working memory in insomnia disorder: Evidence from ERP study |
| title_sort | effect of hypervigilance on visual working memory in insomnia disorder evidence from erp study |
| topic | Insomnia disorder Visual working memory Event-related potentials Hypervigilance |
| url | http://www.sciencedirect.com/science/article/pii/S0361923025003156 |
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