Tuberculosis: The implications for anaesthesia

Tuberculosis is a common problem in South Africa, and provides a number of challenges for the anaesthetist. Patients may present in a variety of ways. Constitutional and pulmonary symptoms are the most common. These may impact on fitness for surgery and choice of anaesthesia. Tuberculosis treatment...

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Main Authors: T.A. Jackson, J.M. Thomas
Format: Article
Language:English
Published: AOSIS 2014-11-01
Series:South African Family Practice
Subjects:
Online Access:https://safpj.co.za/index.php/safpj/article/view/4201
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author T.A. Jackson
J.M. Thomas
author_facet T.A. Jackson
J.M. Thomas
author_sort T.A. Jackson
collection DOAJ
description Tuberculosis is a common problem in South Africa, and provides a number of challenges for the anaesthetist. Patients may present in a variety of ways. Constitutional and pulmonary symptoms are the most common. These may impact on fitness for surgery and choice of anaesthesia. Tuberculosis treatment has the potential for a number of significant drug interactions. These are primarily mediated through induction of the cytochrome P450 enzyme system by rifampicin. Guidelines for the prevention of tuberculosis in the theatre environment need to be followed to avoid placing staff and other patients in danger.
format Article
id doaj-art-94da48dd378b4f188bc9b038e8b56cc5
institution Kabale University
issn 2078-6190
2078-6204
language English
publishDate 2014-11-01
publisher AOSIS
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series South African Family Practice
spelling doaj-art-94da48dd378b4f188bc9b038e8b56cc52025-08-20T03:47:09ZengAOSISSouth African Family Practice2078-61902078-62042014-11-0156610.4102/safp.v56i6.42013392Tuberculosis: The implications for anaesthesiaT.A. Jackson0J.M. Thomas1University of Cape TownRed Cross War Memorial Children’s Hospital, University of Cape TownTuberculosis is a common problem in South Africa, and provides a number of challenges for the anaesthetist. Patients may present in a variety of ways. Constitutional and pulmonary symptoms are the most common. These may impact on fitness for surgery and choice of anaesthesia. Tuberculosis treatment has the potential for a number of significant drug interactions. These are primarily mediated through induction of the cytochrome P450 enzyme system by rifampicin. Guidelines for the prevention of tuberculosis in the theatre environment need to be followed to avoid placing staff and other patients in danger.https://safpj.co.za/index.php/safpj/article/view/4201tuberculosis, antitubercular agents, drug interactions, transmission, bacterial filter
spellingShingle T.A. Jackson
J.M. Thomas
Tuberculosis: The implications for anaesthesia
South African Family Practice
tuberculosis, antitubercular agents, drug interactions, transmission, bacterial filter
title Tuberculosis: The implications for anaesthesia
title_full Tuberculosis: The implications for anaesthesia
title_fullStr Tuberculosis: The implications for anaesthesia
title_full_unstemmed Tuberculosis: The implications for anaesthesia
title_short Tuberculosis: The implications for anaesthesia
title_sort tuberculosis the implications for anaesthesia
topic tuberculosis, antitubercular agents, drug interactions, transmission, bacterial filter
url https://safpj.co.za/index.php/safpj/article/view/4201
work_keys_str_mv AT tajackson tuberculosistheimplicationsforanaesthesia
AT jmthomas tuberculosistheimplicationsforanaesthesia