Sex-Specific Impact of Pain Severity, Insomnia, and Psychosocial Factors on Disability due to Spinal Degenerative Disease

Purpose. Pain experience due to spinal degenerative disease decreases activity of daily living and quality of life. The present cross-sectional study was aimed at examining the sex-specific impact of pain severity, psychosocial factors, and insomnia on the disability due to chronic pain arising from...

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Main Authors: Keito Koh, Keiko Yamada, Tatsuya Enomoto, Aiko Kawai, Saeko Hamaoka, Satoko Chiba, Masako Iseki
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2020/8496527
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author Keito Koh
Keiko Yamada
Tatsuya Enomoto
Aiko Kawai
Saeko Hamaoka
Satoko Chiba
Masako Iseki
author_facet Keito Koh
Keiko Yamada
Tatsuya Enomoto
Aiko Kawai
Saeko Hamaoka
Satoko Chiba
Masako Iseki
author_sort Keito Koh
collection DOAJ
description Purpose. Pain experience due to spinal degenerative disease decreases activity of daily living and quality of life. The present cross-sectional study was aimed at examining the sex-specific impact of pain severity, psychosocial factors, and insomnia on the disability due to chronic pain arising from spinal degenerative disease. Methods. In total, 111 outpatients with chronic spinal degenerative on initial diagnosis were analyzed. The definition of chronic spinal degenerative disease was (1) pain duration ≥3 months, (2) findings of nerve root compression on neurological examination and imaging, and (3) localized neck or lower back pain (not widespread, upper or lower limb pain). We used Numerical Rating Scale (NRS), Pain Disability Assessment Scale (PDAS), Hospital Anxiety and Depression Scale (HADS), Pain Catastrophizing Scale (PCS), and Athens Insomnia Scale (AIS) to assess patients. Univariate regression analysis was performed to investigate whether sex influences the PDAS score, and sex-stratified multivariate regression analysis was conducted to identify the variables associated with the PDAS score. Results. Sex was identified as a predictor of the PDAS score (standardized coefficient (β) = 0.28; 95% confidence interval (CI), 0.10–0.46; p=0.003). In men, the AIS score was associated with PDAS (β = 0.36, 95% CI 0.09–0.63). Age (β = 0.31, 95% CI 0.06–0.55) and NRS (β = 0.40, 95% CI 0.14–0.67) were associated with PDAS in women. HADS-A, HADS-D, and PCS were not associated with PDAS in both sexes. Conclusion. Insomnia was associated with disability in men, whereas aging and pain severity were associated with disability in women. Catastrophic thinking was not associated with disability in both sexes.
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spelling doaj-art-94cd5adb8a9048cab1f59affd2be67f72025-08-20T02:09:48ZengWileyPain Research and Management1203-67651918-15232020-01-01202010.1155/2020/84965278496527Sex-Specific Impact of Pain Severity, Insomnia, and Psychosocial Factors on Disability due to Spinal Degenerative DiseaseKeito Koh0Keiko Yamada1Tatsuya Enomoto2Aiko Kawai3Saeko Hamaoka4Satoko Chiba5Masako Iseki6Department of Anesthesiology and Pain Medicine, Juntendo University Shizuoka Hospital, Izunokuni 410-2211, JapanDepartment of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, Tokyo 113-8431, JapanDepartment of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, Tokyo 113-8431, JapanDepartment of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, Tokyo 113-8431, JapanDepartment of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, Tokyo 113-8431, JapanDepartment of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, Tokyo 113-8431, JapanDepartment of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, Tokyo 113-8431, JapanPurpose. Pain experience due to spinal degenerative disease decreases activity of daily living and quality of life. The present cross-sectional study was aimed at examining the sex-specific impact of pain severity, psychosocial factors, and insomnia on the disability due to chronic pain arising from spinal degenerative disease. Methods. In total, 111 outpatients with chronic spinal degenerative on initial diagnosis were analyzed. The definition of chronic spinal degenerative disease was (1) pain duration ≥3 months, (2) findings of nerve root compression on neurological examination and imaging, and (3) localized neck or lower back pain (not widespread, upper or lower limb pain). We used Numerical Rating Scale (NRS), Pain Disability Assessment Scale (PDAS), Hospital Anxiety and Depression Scale (HADS), Pain Catastrophizing Scale (PCS), and Athens Insomnia Scale (AIS) to assess patients. Univariate regression analysis was performed to investigate whether sex influences the PDAS score, and sex-stratified multivariate regression analysis was conducted to identify the variables associated with the PDAS score. Results. Sex was identified as a predictor of the PDAS score (standardized coefficient (β) = 0.28; 95% confidence interval (CI), 0.10–0.46; p=0.003). In men, the AIS score was associated with PDAS (β = 0.36, 95% CI 0.09–0.63). Age (β = 0.31, 95% CI 0.06–0.55) and NRS (β = 0.40, 95% CI 0.14–0.67) were associated with PDAS in women. HADS-A, HADS-D, and PCS were not associated with PDAS in both sexes. Conclusion. Insomnia was associated with disability in men, whereas aging and pain severity were associated with disability in women. Catastrophic thinking was not associated with disability in both sexes.http://dx.doi.org/10.1155/2020/8496527
spellingShingle Keito Koh
Keiko Yamada
Tatsuya Enomoto
Aiko Kawai
Saeko Hamaoka
Satoko Chiba
Masako Iseki
Sex-Specific Impact of Pain Severity, Insomnia, and Psychosocial Factors on Disability due to Spinal Degenerative Disease
Pain Research and Management
title Sex-Specific Impact of Pain Severity, Insomnia, and Psychosocial Factors on Disability due to Spinal Degenerative Disease
title_full Sex-Specific Impact of Pain Severity, Insomnia, and Psychosocial Factors on Disability due to Spinal Degenerative Disease
title_fullStr Sex-Specific Impact of Pain Severity, Insomnia, and Psychosocial Factors on Disability due to Spinal Degenerative Disease
title_full_unstemmed Sex-Specific Impact of Pain Severity, Insomnia, and Psychosocial Factors on Disability due to Spinal Degenerative Disease
title_short Sex-Specific Impact of Pain Severity, Insomnia, and Psychosocial Factors on Disability due to Spinal Degenerative Disease
title_sort sex specific impact of pain severity insomnia and psychosocial factors on disability due to spinal degenerative disease
url http://dx.doi.org/10.1155/2020/8496527
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