Empowering breast cancer clients through AI chatbots: transforming knowledge and attitudes for enhanced nursing care

Abstract Background Breast cancer remains a leading cause of morbidity worldwide, necessitating innovative and accessible interventions that address both clinical and psychosocial needs. AI-powered chatbots are increasingly used in health education due to their 24/7 availability, personalization, an...

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Main Authors: Mostafa Shaban, Yasmine M. Osman, Nermen Abdelfatah Mohamed, Marwa Mamdouh Shaban
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Nursing
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Online Access:https://doi.org/10.1186/s12912-025-03585-w
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author Mostafa Shaban
Yasmine M. Osman
Nermen Abdelfatah Mohamed
Marwa Mamdouh Shaban
author_facet Mostafa Shaban
Yasmine M. Osman
Nermen Abdelfatah Mohamed
Marwa Mamdouh Shaban
author_sort Mostafa Shaban
collection DOAJ
description Abstract Background Breast cancer remains a leading cause of morbidity worldwide, necessitating innovative and accessible interventions that address both clinical and psychosocial needs. AI-powered chatbots are increasingly used in health education due to their 24/7 availability, personalization, and interactivity. However, empirical evidence on their effectiveness in enhancing knowledge, empowerment, and attitudes in oncology settings remains limited. Aim This randomized controlled trial (RCT) evaluated the impact of an AI chatbot intervention on knowledge, empowerment, and attitudes toward AI among breast cancer patients. Methods A two-arm, pre–post RCT was conducted with 122 women diagnosed with breast cancer at Kafr El-Sheikh University Hospital. Participants were randomly assigned to an intervention group (n = 61) receiving structured AI chatbot-based education plus standard care, or a control group (n = 61) receiving standard care alone. Data were collected using validated questionnaires assessing breast cancer and AI knowledge, attitudes toward AI, and perceived empowerment. G*Power analysis determined sample adequacy for between-group comparisons. Results Post-intervention, the intervention group showed significantly higher knowledge (20.3 ± 2.1 vs. 17.9 ± 3.4, p <.001) and more positive attitudes (82.4 ± 7.2 vs. 72.6 ± 8.9, p <.001) compared to controls. Logistic regression indicated that knowledge gain and higher education predicted a positive AI attitude. Path analysis revealed both direct and mediated effects of knowledge on attitude via empowerment. Usage data and chatbot session logs supported high engagement. Conclusion Integrating AI chatbots into oncology nursing care significantly enhances knowledge, empowerment, and AI acceptance. These findings support chatbot integration in patient-centered digital health strategies, particularly in oncology. Clinical trial number Not applicable. Trial registration NCT06943911 (retrospectively registered on 24/4/2025).
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spelling doaj-art-94ca36dee4c34a63adea366e4fcc1fa42025-08-20T03:42:37ZengBMCBMC Nursing1472-69552025-07-0124111610.1186/s12912-025-03585-wEmpowering breast cancer clients through AI chatbots: transforming knowledge and attitudes for enhanced nursing careMostafa Shaban0Yasmine M. Osman1Nermen Abdelfatah Mohamed2Marwa Mamdouh Shaban3Lecturer of Geriatric Nursing, Faculty of Nursing, Cairo UniversityDepartment of Obstetrics and Gynecology Nursing, Faculty of Nursing, Zagazig UniversityAssistant professor of Adult Nursing Department, Faculty of Nursing, Kafr Elsheikh UniversityLecturer of Community Health Nursing- Faculty of Nursing- Cairo UniversityAbstract Background Breast cancer remains a leading cause of morbidity worldwide, necessitating innovative and accessible interventions that address both clinical and psychosocial needs. AI-powered chatbots are increasingly used in health education due to their 24/7 availability, personalization, and interactivity. However, empirical evidence on their effectiveness in enhancing knowledge, empowerment, and attitudes in oncology settings remains limited. Aim This randomized controlled trial (RCT) evaluated the impact of an AI chatbot intervention on knowledge, empowerment, and attitudes toward AI among breast cancer patients. Methods A two-arm, pre–post RCT was conducted with 122 women diagnosed with breast cancer at Kafr El-Sheikh University Hospital. Participants were randomly assigned to an intervention group (n = 61) receiving structured AI chatbot-based education plus standard care, or a control group (n = 61) receiving standard care alone. Data were collected using validated questionnaires assessing breast cancer and AI knowledge, attitudes toward AI, and perceived empowerment. G*Power analysis determined sample adequacy for between-group comparisons. Results Post-intervention, the intervention group showed significantly higher knowledge (20.3 ± 2.1 vs. 17.9 ± 3.4, p <.001) and more positive attitudes (82.4 ± 7.2 vs. 72.6 ± 8.9, p <.001) compared to controls. Logistic regression indicated that knowledge gain and higher education predicted a positive AI attitude. Path analysis revealed both direct and mediated effects of knowledge on attitude via empowerment. Usage data and chatbot session logs supported high engagement. Conclusion Integrating AI chatbots into oncology nursing care significantly enhances knowledge, empowerment, and AI acceptance. These findings support chatbot integration in patient-centered digital health strategies, particularly in oncology. Clinical trial number Not applicable. Trial registration NCT06943911 (retrospectively registered on 24/4/2025).https://doi.org/10.1186/s12912-025-03585-wBreast cancerAI chatbotEmpowermentPatient educationAttitudesRandomized controlled trial
spellingShingle Mostafa Shaban
Yasmine M. Osman
Nermen Abdelfatah Mohamed
Marwa Mamdouh Shaban
Empowering breast cancer clients through AI chatbots: transforming knowledge and attitudes for enhanced nursing care
BMC Nursing
Breast cancer
AI chatbot
Empowerment
Patient education
Attitudes
Randomized controlled trial
title Empowering breast cancer clients through AI chatbots: transforming knowledge and attitudes for enhanced nursing care
title_full Empowering breast cancer clients through AI chatbots: transforming knowledge and attitudes for enhanced nursing care
title_fullStr Empowering breast cancer clients through AI chatbots: transforming knowledge and attitudes for enhanced nursing care
title_full_unstemmed Empowering breast cancer clients through AI chatbots: transforming knowledge and attitudes for enhanced nursing care
title_short Empowering breast cancer clients through AI chatbots: transforming knowledge and attitudes for enhanced nursing care
title_sort empowering breast cancer clients through ai chatbots transforming knowledge and attitudes for enhanced nursing care
topic Breast cancer
AI chatbot
Empowerment
Patient education
Attitudes
Randomized controlled trial
url https://doi.org/10.1186/s12912-025-03585-w
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