Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling

Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling

Glucocorticoid excess induces apoptosis of islet cells, which may result in diabetes. In this study, we investigated the protective effect of ghrelin on dexamethasone-induced INS-1 cell apoptosis. Our data showed that ghrelin (0.1 μM) inhibited dexamethasone-induced (0.1 μM) apoptosis of INS-1 cells...

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Bibliographic Details
Main Authors:	Chengshuo Zhang, Le Li, Bochao Zhao, Ao Jiao, Xin Li, Ning Sun, Jialin Zhang
Format:	Article
Language:	English
Published:	Wiley 2016-01-01
Series:	International Journal of Endocrinology
Online Access:	http://dx.doi.org/10.1155/2016/4513051
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