SRBD1, a highly conserved gene required for chromosome individualization

Summary: Despite significant progress made in functional genomics, the roles of a relatively small number of essential genes remain enigmatic. Here, we characterize S1 RNA-binding domain-containing protein 1 (SRBD1), an essential gene with no previously assigned function. Through genetic, proteomic,...

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Main Authors:	Jonne A. Raaijmakers, Louise M.E. Janssen, Abdelghani Mazouzi, Amber L.H. Hondema, Razvan Borza, Alexander Fish, Ahmed M.O. Elbatsh, Justina Kazokaitė-Adomaitienė, Nuria Vaquero-Siguero, Isabel Mayayo-Peralta, Leila Nahidiazar, Anoek Friskes, Liesbeth Hoekman, Onno B. Bleijerveld, Claire Hoencamp, Sarah C. Moser, Jos Jonkers, Kees Jalink, Wilbert Zwart, Patrick H.N. Celie, Benjamin D. Rowland, Anastassis Perrakis, Thijn R. Brummelkamp, René H. Medema
Format:	Article
Language:	English
Published:	Elsevier 2025-04-01
Series:	Cell Reports
Subjects:	CP: Molecular biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124725002141
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SRBD1, a highly conserved gene required for chromosome individualization

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