Factors Contributing to Prolonged Time to Extubation After Sevoflurane Anesthesia in Pediatric Patients who Underwent Strabismus Surgery: A Retrospective Study

Background: Rapid and smooth emergence is a crucial factor in the recovery of pediatric patients, especially after short ambulatory surgery. However, the factors contributing to the recovery time in pediatric patients after sevoflurane anesthesia have not yet been established. The present study eval...

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Main Authors: Kyung Mi Kim, Ki Hwa Lee, Jae Hong Park, Ji Yeon Kwon, Yei Heum Park, Jae Hwan Kim
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Bali Journal of Anesthesiology
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Online Access:https://doi.org/10.4103/bjoa.bjoa_243_24
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author Kyung Mi Kim
Ki Hwa Lee
Jae Hong Park
Ji Yeon Kwon
Yei Heum Park
Jae Hwan Kim
author_facet Kyung Mi Kim
Ki Hwa Lee
Jae Hong Park
Ji Yeon Kwon
Yei Heum Park
Jae Hwan Kim
author_sort Kyung Mi Kim
collection DOAJ
description Background: Rapid and smooth emergence is a crucial factor in the recovery of pediatric patients, especially after short ambulatory surgery. However, the factors contributing to the recovery time in pediatric patients after sevoflurane anesthesia have not yet been established. The present study evaluated the underlying factors affecting prolonged extubation time after sevoflurane anesthesia administration. Materials and Methods: Data were collected retrospectively from pediatric patients who underwent strabismus surgery between January 2011 and December 2020. Variables affecting time to extubation, including patient-related, anesthesia-related, and procedure-related factors, were investigated for univariate logistic and multivariate logistic regression analyses. Results: Overall, 459 patients were included in the final analysis. In the univariate analysis, the timing of fentanyl administration (P = 0.001), fentanyl dosage (P = 0.036), and operation/anesthesia duration ratio (P < 0.001) was found to prolong the extubation time significantly. Multiple logistic regression analysis that included intraoperative factors showed that late IV fentanyl administration (odds ratio [OR] = 3.051; 95% confidence interval [CI] = 1.830–5.086), use of a high (>1 µg/kg) fentanyl dose (OR = 2.61; 95% CI = 1.383–4.910), and a low operation/anesthesia duration ratio (OR = 0.92; 95% CI = 0.904–0.945) were associated with late recovery time. Conclusion: Late fentanyl administration, use of a high fentanyl dose, and a low operation/anesthesia duration ratio are potential risk factors for prolonged extubation time after sevoflurane anesthesia administration in pediatric patients.
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spelling doaj-art-94b3b898a2f142bc9bec1053da14e8252025-01-17T10:42:57ZengWolters Kluwer Medknow PublicationsBali Journal of Anesthesiology2549-22762024-12-018422122610.4103/bjoa.bjoa_243_24Factors Contributing to Prolonged Time to Extubation After Sevoflurane Anesthesia in Pediatric Patients who Underwent Strabismus Surgery: A Retrospective StudyKyung Mi KimKi Hwa LeeJae Hong ParkJi Yeon KwonYei Heum ParkJae Hwan KimBackground: Rapid and smooth emergence is a crucial factor in the recovery of pediatric patients, especially after short ambulatory surgery. However, the factors contributing to the recovery time in pediatric patients after sevoflurane anesthesia have not yet been established. The present study evaluated the underlying factors affecting prolonged extubation time after sevoflurane anesthesia administration. Materials and Methods: Data were collected retrospectively from pediatric patients who underwent strabismus surgery between January 2011 and December 2020. Variables affecting time to extubation, including patient-related, anesthesia-related, and procedure-related factors, were investigated for univariate logistic and multivariate logistic regression analyses. Results: Overall, 459 patients were included in the final analysis. In the univariate analysis, the timing of fentanyl administration (P = 0.001), fentanyl dosage (P = 0.036), and operation/anesthesia duration ratio (P < 0.001) was found to prolong the extubation time significantly. Multiple logistic regression analysis that included intraoperative factors showed that late IV fentanyl administration (odds ratio [OR] = 3.051; 95% confidence interval [CI] = 1.830–5.086), use of a high (>1 µg/kg) fentanyl dose (OR = 2.61; 95% CI = 1.383–4.910), and a low operation/anesthesia duration ratio (OR = 0.92; 95% CI = 0.904–0.945) were associated with late recovery time. Conclusion: Late fentanyl administration, use of a high fentanyl dose, and a low operation/anesthesia duration ratio are potential risk factors for prolonged extubation time after sevoflurane anesthesia administration in pediatric patients.https://doi.org/10.4103/bjoa.bjoa_243_24delayed awakeningfentanylpediatricssevoflurane
spellingShingle Kyung Mi Kim
Ki Hwa Lee
Jae Hong Park
Ji Yeon Kwon
Yei Heum Park
Jae Hwan Kim
Factors Contributing to Prolonged Time to Extubation After Sevoflurane Anesthesia in Pediatric Patients who Underwent Strabismus Surgery: A Retrospective Study
Bali Journal of Anesthesiology
delayed awakening
fentanyl
pediatrics
sevoflurane
title Factors Contributing to Prolonged Time to Extubation After Sevoflurane Anesthesia in Pediatric Patients who Underwent Strabismus Surgery: A Retrospective Study
title_full Factors Contributing to Prolonged Time to Extubation After Sevoflurane Anesthesia in Pediatric Patients who Underwent Strabismus Surgery: A Retrospective Study
title_fullStr Factors Contributing to Prolonged Time to Extubation After Sevoflurane Anesthesia in Pediatric Patients who Underwent Strabismus Surgery: A Retrospective Study
title_full_unstemmed Factors Contributing to Prolonged Time to Extubation After Sevoflurane Anesthesia in Pediatric Patients who Underwent Strabismus Surgery: A Retrospective Study
title_short Factors Contributing to Prolonged Time to Extubation After Sevoflurane Anesthesia in Pediatric Patients who Underwent Strabismus Surgery: A Retrospective Study
title_sort factors contributing to prolonged time to extubation after sevoflurane anesthesia in pediatric patients who underwent strabismus surgery a retrospective study
topic delayed awakening
fentanyl
pediatrics
sevoflurane
url https://doi.org/10.4103/bjoa.bjoa_243_24
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