Efficacy and safety of medroxyprogesterone acetate on noninvasive ventilation -treated exacerbated COPD patients: a double-blind randomized clinical trial

Efficacy and safety of medroxyprogesterone acetate on noninvasive ventilation -treated exacerbated COPD patients: a double-blind randomized clinical trial

Abstract Background In acute exacerbation periods of chronic obstructive pulmonary disease (COPD), patients may experience hypoxemia or hypercapnia. Noninvasive ventilation (NIV) and respiratory stimulant drugs are used to treat this condition. Medroxyprogesterone acetate (MPA) can cross the blood-b...

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Bibliographic Details
Main Authors: Mohsen Gholinataj Jelodar, Mohammadreza Malek-Ahmadi, Adeleh Sahebnasagh, Farhad Mohammadi, Fatemeh Saghafi
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Pulmonary Medicine
Subjects:
COPD
Exacerbation
Hypercapnia
NIV
Medroxyprogesterone acetate
RCT
Online Access:https://doi.org/10.1186/s12890-024-03462-3
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