Oedematic-atrophic astrocytes in hepatic encephalopathy

Oedematic-atrophic astrocytes in hepatic encephalopathy

Abstract Hepatic encephalopathy (HE) following acute liver failure (ALF) is considered as a primary toxic astrocytopathy, but in-depth characterisation of astrocytic contribution to the pathogenesis of this disease is far from complete. Using transmission electron microscopy, confocal fluorescent mi...

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Main Authors: Mariusz Popek, Marta Obara-Michlewska, Łukasz Mateusz Szewczyk, Marcin Kołodziej, Karol Perlejewski, Alexei Verkhratsky, Jan Albrecht, Magdalena Zielińska
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Acta Neuropathologica Communications
Subjects:
Astrocyte
Acute liver failure
Aquaporin 4
Ezrin
Profilin-1
Online Access:https://doi.org/10.1186/s40478-025-02045-5
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https://doi.org/10.1186/s40478-025-02045-5

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