Transcriptomic mortality signature defines high-risk neonatal sepsis endotype

Transcriptomic mortality signature defines high-risk neonatal sepsis endotype

IntroductionNeonatal sepsis remains a leading cause of global childhood mortality, yet treatment options are limited. Clinical and biological heterogeneity hinders the development of targeted therapies. Gene-expression profiling offers a potential strategy to identify neonatal sepsis subtypes and gu...

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Bibliographic Details
Main Authors: Faris N. Al Gharaibeh, Min Huang, James L. Wynn, Rishikesan Kamaleswaran, Mihir R. Atreya
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
neonatal sepsis
mortality
gene-expression profiling
endotypes
neutrophils
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1601316/full
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