The role of bile acid metabolism-related genes in prognosis assessment of hepatocellular carcinoma and identification of NPC1 as a biomarker

The role of bile acid metabolism-related genes in prognosis assessment of hepatocellular carcinoma and identification of NPC1 as a biomarker

Hepatocellular carcinoma (HCC) is one of the most prevalent and deadly cancers worldwide, with a high recurrence rate and poor prognosis. Understanding the molecular mechanisms driving HCC progression is crucial for improving prognostic accuracy and developing targeted therapies. Bile acids (BAs), a...

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Bibliographic Details
Main Authors: Maosen Xu, Yu Zhang, Yan Tie, Yiqiao Luo, Yang Wang, Ziqi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Endocrinology
Subjects:
hepatocellular carcinoma
bile acids metabolism
NPC1
tumor microenvironment
immune
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1588529/full
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