Hormonal Disharmony—A Rare Case of Catamenial Cyclical Vomiting Syndrome
Cyclic vomiting syndrome (CVS) is a rare and enfeebling neuroendocrine disorder mostly seen in children. It is characterized by recurrent episodes of nausea and vomiting with interepisodic normal periods. There are various triggers for an episode among which menstruation is one critical trigger. A m...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-04-01
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| Series: | Journal of Psychosexual Health |
| Online Access: | https://doi.org/10.1177/26318318251322047 |
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| author | Souganya Vijayan Barath Ramanathan Arun Selvaraj Ponmani Elangovan |
| author_facet | Souganya Vijayan Barath Ramanathan Arun Selvaraj Ponmani Elangovan |
| author_sort | Souganya Vijayan |
| collection | DOAJ |
| description | Cyclic vomiting syndrome (CVS) is a rare and enfeebling neuroendocrine disorder mostly seen in children. It is characterized by recurrent episodes of nausea and vomiting with interepisodic normal periods. There are various triggers for an episode among which menstruation is one critical trigger. A majority of childhood-onset CVS attain remission by teenage or before puberty. There is neurophysiological evidence to associate cyclical vomiting with migraine. It is also supported clinically by the presence of aura and photophobia. The fluctuation in estrogen and progesterone levels during the menstrual cycle is proposed to be the pathophysiological basis of catamenial CVS, which is shared by catamenial migraine. The diagnosis of cyclical vomiting is essentially clinical. Management comprises of acute stage followed by chronic stage. The acute management is targeted to abort the current episode and correct the fluid and electrolyte imbalance. Sumatriptan is found to be effective in the termination of an acute episode. Intravenous fluid and electrolyte replacement are critical. The second step is planning a prophylactic treatment strategy to prevent further episodes. Tricyclic antidepressants are extensively used and are found to be effective. Considering the background of hormonal fluctuation in catamenial cyclical vomiting, hormone replacement therapy with oral and transdermal patches has been attempted with positive results. Any chronic vomiting with inconclusive findings in investigations must raise suspicion regarding CVS. Early identification and treatment considerably improve the quality of life. |
| format | Article |
| id | doaj-art-949bb63d3d674ee7b5b183c2f5745462 |
| institution | Kabale University |
| issn | 2631-8318 2631-8326 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Psychosexual Health |
| spelling | doaj-art-949bb63d3d674ee7b5b183c2f57454622025-08-20T03:26:56ZengSAGE PublishingJournal of Psychosexual Health2631-83182631-83262025-04-01710.1177/26318318251322047Hormonal Disharmony—A Rare Case of Catamenial Cyclical Vomiting SyndromeSouganya Vijayan0Barath Ramanathan1Arun Selvaraj2Ponmani Elangovan3 Sri Manakula Vinayagar Medical College and Hospital, Pondicherry, India Sri Manakula Vinayagar Medical College and Hospital, Pondicherry, India Sri Manakula Vinayagar Medical College and Hospital, Pondicherry, India Department of Psychiatry, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, IndiaCyclic vomiting syndrome (CVS) is a rare and enfeebling neuroendocrine disorder mostly seen in children. It is characterized by recurrent episodes of nausea and vomiting with interepisodic normal periods. There are various triggers for an episode among which menstruation is one critical trigger. A majority of childhood-onset CVS attain remission by teenage or before puberty. There is neurophysiological evidence to associate cyclical vomiting with migraine. It is also supported clinically by the presence of aura and photophobia. The fluctuation in estrogen and progesterone levels during the menstrual cycle is proposed to be the pathophysiological basis of catamenial CVS, which is shared by catamenial migraine. The diagnosis of cyclical vomiting is essentially clinical. Management comprises of acute stage followed by chronic stage. The acute management is targeted to abort the current episode and correct the fluid and electrolyte imbalance. Sumatriptan is found to be effective in the termination of an acute episode. Intravenous fluid and electrolyte replacement are critical. The second step is planning a prophylactic treatment strategy to prevent further episodes. Tricyclic antidepressants are extensively used and are found to be effective. Considering the background of hormonal fluctuation in catamenial cyclical vomiting, hormone replacement therapy with oral and transdermal patches has been attempted with positive results. Any chronic vomiting with inconclusive findings in investigations must raise suspicion regarding CVS. Early identification and treatment considerably improve the quality of life.https://doi.org/10.1177/26318318251322047 |
| spellingShingle | Souganya Vijayan Barath Ramanathan Arun Selvaraj Ponmani Elangovan Hormonal Disharmony—A Rare Case of Catamenial Cyclical Vomiting Syndrome Journal of Psychosexual Health |
| title | Hormonal Disharmony—A Rare Case of Catamenial Cyclical Vomiting Syndrome |
| title_full | Hormonal Disharmony—A Rare Case of Catamenial Cyclical Vomiting Syndrome |
| title_fullStr | Hormonal Disharmony—A Rare Case of Catamenial Cyclical Vomiting Syndrome |
| title_full_unstemmed | Hormonal Disharmony—A Rare Case of Catamenial Cyclical Vomiting Syndrome |
| title_short | Hormonal Disharmony—A Rare Case of Catamenial Cyclical Vomiting Syndrome |
| title_sort | hormonal disharmony a rare case of catamenial cyclical vomiting syndrome |
| url | https://doi.org/10.1177/26318318251322047 |
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