An analysis of 60 years of autopsy data from Zhejiang university in Hangzhou, China.
<h4>Context</h4>The autopsy rate gradually decreased during 1950-1999, and increased during the most recent decade (2000-2009). The diagnostic inaccuracy rate was continuously high during the 60 years.<h4>Objective</h4>To investigate disagreement between the pathological and...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0112500&type=printable |
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| Summary: | <h4>Context</h4>The autopsy rate gradually decreased during 1950-1999, and increased during the most recent decade (2000-2009). The diagnostic inaccuracy rate was continuously high during the 60 years.<h4>Objective</h4>To investigate disagreement between the pathological and clinical diagnosis during 60 years (1950-2009).<h4>Data sources</h4>A 60-year retrospective study was carried out on the 4140 autopsy cases performed in Zhejiang University School of Medicine.<h4>Results</h4>The highest number of cases was 1037 during 1960-1969, while the lowest was 102 during 1990-1999. During the 1999-2009 period, 978 cases were completed, which ranked second within the 60 years. The total clinical misdiagnosis rate was 46.38%, while the highest was 73.82% in 2000-2009. During the 60 years, the diseases associated with highest diagnostic inaccuracy rates were circulatory diseases (76.97%), cancer (60.99%), and brain diseases (54.48%). The invasive fungal infection rate was 1.84% of the 4140 cases, and the diagnostic inaccuracy rate for this condition reached as high as 86.10%. In the autopsied disease spectrum over the 60 years, the most common diseases were respiratory (1349, 32.58%), circulatory (495, 11.96%), and brain diseases (424, 10.24%).<h4>Conclusion</h4>Although the number of autopsies decreased from 1950 to 1999, it increased from 2000 to 2009, while the discordance rate between clinical and autopsy diagnosis remained high throughout. |
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| ISSN: | 1932-6203 |