Abnormalities of the endocannabinoid system produce piercing nuclear hernias in migrating cerebral neurons

Summary: We are reporting powerful streams of chromatin rupturing the nuclear envelope (NE) and the plasma membrane of migrating cerebral neurons in mouse embryos, which we suggest naming “piercing nuclear hernia” (PNH). About 40% of migrating neurons in cannabinoid type 1 receptor knock-out (CB1R−/...

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Bibliographic Details
Main Authors: Yury M. Morozov, Pasko Rakic
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S258900422501449X
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