Evaluation of nutritional intake and malnutrition in critically ill patients and its relationship with 28-day death

Abstract Malnutrition and risk for malnutrition in critically ill patients are associated with adverse outcomes. However, the adequacy of nutrient intake and its impact on malnutrition have not been entirely determined in previous studies. Above all, this study investigates the relationship between...

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Main Authors: Mohsen Rezaeian, Shiva Monfared-Parizi, Zahra Mousavi Shirazifard, Ahmadreza Sayadi, Hassan Khodadadi, Maryam Ghaseminasab-Parizi
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-00780-2
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author Mohsen Rezaeian
Shiva Monfared-Parizi
Zahra Mousavi Shirazifard
Ahmadreza Sayadi
Hassan Khodadadi
Maryam Ghaseminasab-Parizi
author_facet Mohsen Rezaeian
Shiva Monfared-Parizi
Zahra Mousavi Shirazifard
Ahmadreza Sayadi
Hassan Khodadadi
Maryam Ghaseminasab-Parizi
author_sort Mohsen Rezaeian
collection DOAJ
description Abstract Malnutrition and risk for malnutrition in critically ill patients are associated with adverse outcomes. However, the adequacy of nutrient intake and its impact on malnutrition have not been entirely determined in previous studies. Above all, this study investigates the relationship between some nutrient intake and malnutrition levels and 28-day death. The observational study was done on patients over 18 years of age in Rafsanjan Intensive Care Unit (ICU) from April 21 to October 24, 2022. Subjective global assessment (SGA), modified nutrition risk in critically Ill (mNUTRIC) Score, demographic details and intake of some nutrients were assessed. Data was analyzed with SPSS 22 software, and a p-value of 0.05 was a significant level for all analysis.118 patients were studied. Malnutrition and mNUTRIC score are linked to 28-day mortality in logistic regression analysis (OR: 3.63, 95%CI 1.48–8.91, p = 0.004 and OR: 12.69, 95%CI 4.42–36.43, p < 0.001, respectively). There was no significant difference between the intake of some nutrients and malnutrition/ risk for malnutrition. This study reveals no relevance between nutrient intake with malnutrition and risk for malnutrition. Moreover, in malnourished patients, some nutrient intake was unrelated to the 28-day death. It is suggested that future studies be done with a larger sample size.
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spelling doaj-art-9494850e3d04495db8ecbe1bce18c2b62025-08-20T03:09:35ZengNature PortfolioScientific Reports2045-23222025-05-011511810.1038/s41598-025-00780-2Evaluation of nutritional intake and malnutrition in critically ill patients and its relationship with 28-day deathMohsen Rezaeian0Shiva Monfared-Parizi1Zahra Mousavi Shirazifard2Ahmadreza Sayadi3Hassan Khodadadi4Maryam Ghaseminasab-Parizi5Department of Epidemiology and Biostatistics, Occupational Environment Research Center, School of Health, Rafsanjan University of Medical SciencesHospital of Aliebneabitaleb, Rafsanjan University of Medical SciencesNutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical SciencesDepartment of Psychiatric Nursing, Social Determinants of Health Research Center, School of Nursing and Midwifery, University of Medical SciencesDepartment of Health in Disasters and Emergencies, School of Health, Rafsanjan University of Medical SciencesDepartment of Health Education and Health Promotion, Occupational Environment Research Center, School of Health, Rafsanjan University of Medical SciencesAbstract Malnutrition and risk for malnutrition in critically ill patients are associated with adverse outcomes. However, the adequacy of nutrient intake and its impact on malnutrition have not been entirely determined in previous studies. Above all, this study investigates the relationship between some nutrient intake and malnutrition levels and 28-day death. The observational study was done on patients over 18 years of age in Rafsanjan Intensive Care Unit (ICU) from April 21 to October 24, 2022. Subjective global assessment (SGA), modified nutrition risk in critically Ill (mNUTRIC) Score, demographic details and intake of some nutrients were assessed. Data was analyzed with SPSS 22 software, and a p-value of 0.05 was a significant level for all analysis.118 patients were studied. Malnutrition and mNUTRIC score are linked to 28-day mortality in logistic regression analysis (OR: 3.63, 95%CI 1.48–8.91, p = 0.004 and OR: 12.69, 95%CI 4.42–36.43, p < 0.001, respectively). There was no significant difference between the intake of some nutrients and malnutrition/ risk for malnutrition. This study reveals no relevance between nutrient intake with malnutrition and risk for malnutrition. Moreover, in malnourished patients, some nutrient intake was unrelated to the 28-day death. It is suggested that future studies be done with a larger sample size.https://doi.org/10.1038/s41598-025-00780-2MalnutritionIntensive care unitNutrition assessmentDietary intakeRisk for malnutrition
spellingShingle Mohsen Rezaeian
Shiva Monfared-Parizi
Zahra Mousavi Shirazifard
Ahmadreza Sayadi
Hassan Khodadadi
Maryam Ghaseminasab-Parizi
Evaluation of nutritional intake and malnutrition in critically ill patients and its relationship with 28-day death
Scientific Reports
Malnutrition
Intensive care unit
Nutrition assessment
Dietary intake
Risk for malnutrition
title Evaluation of nutritional intake and malnutrition in critically ill patients and its relationship with 28-day death
title_full Evaluation of nutritional intake and malnutrition in critically ill patients and its relationship with 28-day death
title_fullStr Evaluation of nutritional intake and malnutrition in critically ill patients and its relationship with 28-day death
title_full_unstemmed Evaluation of nutritional intake and malnutrition in critically ill patients and its relationship with 28-day death
title_short Evaluation of nutritional intake and malnutrition in critically ill patients and its relationship with 28-day death
title_sort evaluation of nutritional intake and malnutrition in critically ill patients and its relationship with 28 day death
topic Malnutrition
Intensive care unit
Nutrition assessment
Dietary intake
Risk for malnutrition
url https://doi.org/10.1038/s41598-025-00780-2
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