Advancement in public health through machine learning: a narrative review of opportunities and ethical considerations

Abstract This narrative review presents a comprehensive and state-of-the-art synthesis of how machine learning (ML) is transforming public health through enhanced prediction, personalized treatment, real-time surveillance, and intelligent resource optimization. Drawing from 170 peer-reviewed studies...

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Main Authors: Sumit Singh Dhanda, Deepak Panwar, Chia-Chen Lin, Tarun Kumar Sharma, Deependra Rastogi, Shantanu Bindewari, Anand Singh, Yung-Hui Li, Neha Agarwal, Saurabh Agarwal
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:Journal of Big Data
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Online Access:https://doi.org/10.1186/s40537-025-01201-x
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author Sumit Singh Dhanda
Deepak Panwar
Chia-Chen Lin
Tarun Kumar Sharma
Deependra Rastogi
Shantanu Bindewari
Anand Singh
Yung-Hui Li
Neha Agarwal
Saurabh Agarwal
author_facet Sumit Singh Dhanda
Deepak Panwar
Chia-Chen Lin
Tarun Kumar Sharma
Deependra Rastogi
Shantanu Bindewari
Anand Singh
Yung-Hui Li
Neha Agarwal
Saurabh Agarwal
author_sort Sumit Singh Dhanda
collection DOAJ
description Abstract This narrative review presents a comprehensive and state-of-the-art synthesis of how machine learning (ML) is transforming public health through enhanced prediction, personalized treatment, real-time surveillance, and intelligent resource optimization. Drawing from 170 peer-reviewed studies published up to 2024/2025, this work uniquely integrates cross-domain insights spanning disease outbreak forecasting, genomic data analysis, personalized medicine, mental health monitoring, and public health infrastructure planning. The novelty of this review lies in its multidimensionality. It merges technical efficacy, ethical challenges, and future trends into a unified narrative. Our findings show substantial performance gains across domains: for example, ML models such as LightGBM, GRU neural networks, and LSTM achieved disease prediction accuracies ranging from 88 to 95%. In genomics, ML methods enabled nuanced disease subtype discovery and improved the accuracy of cancer risk assessment and pharmacogenomic modeling. Mental health prediction systems based on NLP and wearable data delivered up to 91% accuracy in stress and depression detection, while hospital resource forecasting models using deep learning minimized errors in predicting emergency admissions. Ethically, this review surfaces critical issues, including algorithmic bias, data privacy concerns in mental health analytics, and the interpretability of black-box models used in outbreak surveillance. A forward-looking discussion identifies future priorities such as the integration of multi-omics data, deployment of explainable AI, and equitable data inclusion frameworks. This review stands out by not only cataloguing applications but also offering a systems-level perspective on how ML can equitably and ethically scale to support public health strategies globally. It is among the first narrative reviews to concurrently evaluate ML’s predictive power, ethical constraints, and domain-specific improvements across all core pillars of public health.
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spelling doaj-art-948b782633604fe2b774dde1822597b32025-08-20T03:45:30ZengSpringerOpenJournal of Big Data2196-11152025-07-0112115810.1186/s40537-025-01201-xAdvancement in public health through machine learning: a narrative review of opportunities and ethical considerationsSumit Singh Dhanda0Deepak Panwar1Chia-Chen Lin2Tarun Kumar Sharma3Deependra Rastogi4Shantanu Bindewari5Anand Singh6Yung-Hui Li7Neha Agarwal8Saurabh Agarwal9School of Computer Science and Engineering, IILM UniversityManipal University JaipurDepartment of Computer Science and Information Engineering, National Chin-Yi University of TechnologySchool of Computer Science and Engineering, Shobhit UniversitySchool of Computer Science and Engineering, IILM UniversitySchool of Computer Science and Engineering, IILM UniversitySchool of Computer Science and Engineering, IILM UniversityAI Research Center, Hon Hai Research InstituteSchool of Chemical Engineering, Yeungnam UniversitySchool of Computer Science and Engineering, Yeungnam UniversityAbstract This narrative review presents a comprehensive and state-of-the-art synthesis of how machine learning (ML) is transforming public health through enhanced prediction, personalized treatment, real-time surveillance, and intelligent resource optimization. Drawing from 170 peer-reviewed studies published up to 2024/2025, this work uniquely integrates cross-domain insights spanning disease outbreak forecasting, genomic data analysis, personalized medicine, mental health monitoring, and public health infrastructure planning. The novelty of this review lies in its multidimensionality. It merges technical efficacy, ethical challenges, and future trends into a unified narrative. Our findings show substantial performance gains across domains: for example, ML models such as LightGBM, GRU neural networks, and LSTM achieved disease prediction accuracies ranging from 88 to 95%. In genomics, ML methods enabled nuanced disease subtype discovery and improved the accuracy of cancer risk assessment and pharmacogenomic modeling. Mental health prediction systems based on NLP and wearable data delivered up to 91% accuracy in stress and depression detection, while hospital resource forecasting models using deep learning minimized errors in predicting emergency admissions. Ethically, this review surfaces critical issues, including algorithmic bias, data privacy concerns in mental health analytics, and the interpretability of black-box models used in outbreak surveillance. A forward-looking discussion identifies future priorities such as the integration of multi-omics data, deployment of explainable AI, and equitable data inclusion frameworks. This review stands out by not only cataloguing applications but also offering a systems-level perspective on how ML can equitably and ethically scale to support public health strategies globally. It is among the first narrative reviews to concurrently evaluate ML’s predictive power, ethical constraints, and domain-specific improvements across all core pillars of public health.https://doi.org/10.1186/s40537-025-01201-xPublic healthMachine learningArtificial intelligencePersonalized medicineMental healthResource allocation and optimization
spellingShingle Sumit Singh Dhanda
Deepak Panwar
Chia-Chen Lin
Tarun Kumar Sharma
Deependra Rastogi
Shantanu Bindewari
Anand Singh
Yung-Hui Li
Neha Agarwal
Saurabh Agarwal
Advancement in public health through machine learning: a narrative review of opportunities and ethical considerations
Journal of Big Data
Public health
Machine learning
Artificial intelligence
Personalized medicine
Mental health
Resource allocation and optimization
title Advancement in public health through machine learning: a narrative review of opportunities and ethical considerations
title_full Advancement in public health through machine learning: a narrative review of opportunities and ethical considerations
title_fullStr Advancement in public health through machine learning: a narrative review of opportunities and ethical considerations
title_full_unstemmed Advancement in public health through machine learning: a narrative review of opportunities and ethical considerations
title_short Advancement in public health through machine learning: a narrative review of opportunities and ethical considerations
title_sort advancement in public health through machine learning a narrative review of opportunities and ethical considerations
topic Public health
Machine learning
Artificial intelligence
Personalized medicine
Mental health
Resource allocation and optimization
url https://doi.org/10.1186/s40537-025-01201-x
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