Post-COVID-19 severe pneumonia in a non-HIV and immunocompetent patient: A case report and literature review

Pneumocystis jirovecii is a ubiquitous opportunistic fungus that can cause life-threatening pneumonia. The clinical manifestations of pneumonia caused by severe acute respiratory syndrome coronavirus 2 and P. jirovecii are similar, posing a significant challenge in the diagnosis of P. jirovecii pneu...

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Main Authors: Zhi-Yang Xu, Wei Ouyang, Jin-Liang Liu, Wen-Jing Ye, Feng Xu
Format: Article
Language:English
Published: SAGE Publishing 2025-06-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605251344140
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author Zhi-Yang Xu
Wei Ouyang
Jin-Liang Liu
Wen-Jing Ye
Feng Xu
author_facet Zhi-Yang Xu
Wei Ouyang
Jin-Liang Liu
Wen-Jing Ye
Feng Xu
author_sort Zhi-Yang Xu
collection DOAJ
description Pneumocystis jirovecii is a ubiquitous opportunistic fungus that can cause life-threatening pneumonia. The clinical manifestations of pneumonia caused by severe acute respiratory syndrome coronavirus 2 and P. jirovecii are similar, posing a significant challenge in the diagnosis of P. jirovecii pneumonia or coronavirus disease 2019. Herein, we report a case of P. jirovecii pneumonia diagnosed through bronchoalveolar lavage and sputum smear analyses. The patient recovered successfully and was discharged following combination therapy with trimethoprim/sulfamethoxazole and corticosteroids. Early diagnosis and prompt treatment are of vital importance in managing P. jirovecii pneumonia, particularly in individuals with related risk factors for P. jirovecii pneumonia development.
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id doaj-art-9489bda6f5e24fc9ad19f3d19b42a246
institution Kabale University
issn 1473-2300
language English
publishDate 2025-06-01
publisher SAGE Publishing
record_format Article
series Journal of International Medical Research
spelling doaj-art-9489bda6f5e24fc9ad19f3d19b42a2462025-08-20T03:45:31ZengSAGE PublishingJournal of International Medical Research1473-23002025-06-015310.1177/03000605251344140Post-COVID-19 severe pneumonia in a non-HIV and immunocompetent patient: A case report and literature reviewZhi-Yang XuWei OuyangJin-Liang LiuWen-Jing YeFeng XuPneumocystis jirovecii is a ubiquitous opportunistic fungus that can cause life-threatening pneumonia. The clinical manifestations of pneumonia caused by severe acute respiratory syndrome coronavirus 2 and P. jirovecii are similar, posing a significant challenge in the diagnosis of P. jirovecii pneumonia or coronavirus disease 2019. Herein, we report a case of P. jirovecii pneumonia diagnosed through bronchoalveolar lavage and sputum smear analyses. The patient recovered successfully and was discharged following combination therapy with trimethoprim/sulfamethoxazole and corticosteroids. Early diagnosis and prompt treatment are of vital importance in managing P. jirovecii pneumonia, particularly in individuals with related risk factors for P. jirovecii pneumonia development.https://doi.org/10.1177/03000605251344140
spellingShingle Zhi-Yang Xu
Wei Ouyang
Jin-Liang Liu
Wen-Jing Ye
Feng Xu
Post-COVID-19 severe pneumonia in a non-HIV and immunocompetent patient: A case report and literature review
Journal of International Medical Research
title Post-COVID-19 severe pneumonia in a non-HIV and immunocompetent patient: A case report and literature review
title_full Post-COVID-19 severe pneumonia in a non-HIV and immunocompetent patient: A case report and literature review
title_fullStr Post-COVID-19 severe pneumonia in a non-HIV and immunocompetent patient: A case report and literature review
title_full_unstemmed Post-COVID-19 severe pneumonia in a non-HIV and immunocompetent patient: A case report and literature review
title_short Post-COVID-19 severe pneumonia in a non-HIV and immunocompetent patient: A case report and literature review
title_sort post covid 19 severe pneumonia in a non hiv and immunocompetent patient a case report and literature review
url https://doi.org/10.1177/03000605251344140
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