Maxillary Sinus Natural Killer/T-Cell Extranodal Lymphoma Mimicking a Dentoalveolar Abscess

Extranodal natural killer/T-cell lymphoma (ENKL) is an aggressive and infrequent malignant neoplasm. Early sinonasal ENKL clinical symptomatology is often not specific which can mimic several clinical odontogenic processes such as dentoalveolar abscesses. A 41-year-old female was referred to our ins...

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Main Authors: Erika Antonia dos Anjos Ramos, Luciana Munhoz, Basílio Almeida Milani, Tomás Zecchini Barrese, Stephanie Kenig Viveiros, Emiko Saito Arita
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2019/6701783
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author Erika Antonia dos Anjos Ramos
Luciana Munhoz
Basílio Almeida Milani
Tomás Zecchini Barrese
Stephanie Kenig Viveiros
Emiko Saito Arita
author_facet Erika Antonia dos Anjos Ramos
Luciana Munhoz
Basílio Almeida Milani
Tomás Zecchini Barrese
Stephanie Kenig Viveiros
Emiko Saito Arita
author_sort Erika Antonia dos Anjos Ramos
collection DOAJ
description Extranodal natural killer/T-cell lymphoma (ENKL) is an aggressive and infrequent malignant neoplasm. Early sinonasal ENKL clinical symptomatology is often not specific which can mimic several clinical odontogenic processes such as dentoalveolar abscesses. A 41-year-old female was referred to our institution due to facial pain with skin rash, fever, and intraoral swelling in the left side of the maxillary region. Computed tomography (CT) revealed a soft tissue hypodense area in the left side with bone discontinuity in anterior and lateral maxillary sinuses. Initial laboratorial tests showed no alterations on hemogram, coagulation profile, and immune phenotype (CD3+/CD4+). However, the lesion progressed fastly showing an evident growth, so it was decided that an intraoral biopsy should be performed. The diagnosis was sinonasal ENKLs. This case is an example that the rare T-cell lymphoma can mimic an odontogenic lesion, thus puzzling the clinician. Fortunately, the rapid growth of the lesion prompted the correct diagnosis and early treatment.
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publishDate 2019-01-01
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series Case Reports in Dentistry
spelling doaj-art-9483fbfb0e6c4f6d9e66c0f27c01a5af2025-02-03T05:47:59ZengWileyCase Reports in Dentistry2090-64472090-64552019-01-01201910.1155/2019/67017836701783Maxillary Sinus Natural Killer/T-Cell Extranodal Lymphoma Mimicking a Dentoalveolar AbscessErika Antonia dos Anjos Ramos0Luciana Munhoz1Basílio Almeida Milani2Tomás Zecchini Barrese3Stephanie Kenig Viveiros4Emiko Saito Arita5Department of Stomatology, School of Dentistry, University of São Paulo, 2227 Lineu Prestes Avenue, 05508-000 São Paulo, SP, BrazilDepartment of Stomatology, School of Dentistry, University of São Paulo, 2227 Lineu Prestes Avenue, 05508-000 São Paulo, SP, BrazilDepartment of Maxillofacial Surgery, Hospital Municipal do Campo Limpo, 1661 Estrada da Itapecerica, 05835-005 São Paulo, BrazilDepartment of Pathological Sciences, School of Medicine, Santa Casa de Sao Paulo School of Medical Sciences, 61 Dr. Cesário Motta Junior Street, 01221-020 São Paulo, SP, BrazilDepartment of Stomatology, School of Dentistry, University of São Paulo, 2227 Lineu Prestes Avenue, 05508-000 São Paulo, SP, BrazilDepartment of Stomatology, School of Dentistry, University of São Paulo, 2227 Lineu Prestes Avenue, 05508-000 São Paulo, SP, BrazilExtranodal natural killer/T-cell lymphoma (ENKL) is an aggressive and infrequent malignant neoplasm. Early sinonasal ENKL clinical symptomatology is often not specific which can mimic several clinical odontogenic processes such as dentoalveolar abscesses. A 41-year-old female was referred to our institution due to facial pain with skin rash, fever, and intraoral swelling in the left side of the maxillary region. Computed tomography (CT) revealed a soft tissue hypodense area in the left side with bone discontinuity in anterior and lateral maxillary sinuses. Initial laboratorial tests showed no alterations on hemogram, coagulation profile, and immune phenotype (CD3+/CD4+). However, the lesion progressed fastly showing an evident growth, so it was decided that an intraoral biopsy should be performed. The diagnosis was sinonasal ENKLs. This case is an example that the rare T-cell lymphoma can mimic an odontogenic lesion, thus puzzling the clinician. Fortunately, the rapid growth of the lesion prompted the correct diagnosis and early treatment.http://dx.doi.org/10.1155/2019/6701783
spellingShingle Erika Antonia dos Anjos Ramos
Luciana Munhoz
Basílio Almeida Milani
Tomás Zecchini Barrese
Stephanie Kenig Viveiros
Emiko Saito Arita
Maxillary Sinus Natural Killer/T-Cell Extranodal Lymphoma Mimicking a Dentoalveolar Abscess
Case Reports in Dentistry
title Maxillary Sinus Natural Killer/T-Cell Extranodal Lymphoma Mimicking a Dentoalveolar Abscess
title_full Maxillary Sinus Natural Killer/T-Cell Extranodal Lymphoma Mimicking a Dentoalveolar Abscess
title_fullStr Maxillary Sinus Natural Killer/T-Cell Extranodal Lymphoma Mimicking a Dentoalveolar Abscess
title_full_unstemmed Maxillary Sinus Natural Killer/T-Cell Extranodal Lymphoma Mimicking a Dentoalveolar Abscess
title_short Maxillary Sinus Natural Killer/T-Cell Extranodal Lymphoma Mimicking a Dentoalveolar Abscess
title_sort maxillary sinus natural killer t cell extranodal lymphoma mimicking a dentoalveolar abscess
url http://dx.doi.org/10.1155/2019/6701783
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