Cholesterol metabolism and neuroinflammatory changes in a non-human primate spinal nerve ligation model

Cholesterol metabolism and neuroinflammatory changes in a non-human primate spinal nerve ligation model

Abstract Neuropathic pain remains one of the major neurological conditions with high unmet medical needs. Poor translation from preclinical studies using rodent models to clinical trials is one of the major obstacles to the development of new pharmacological medications to treat neuropathic pain. Th...

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Bibliographic Details
Main Authors: Hiroshi Yamane, Suguru Koyama, Takayuki Komatsu, Tomoya Tanaka, Riyu Koguchi, Haruhisa Watanabe, Mai Nishiura, Satoru Yoshikawa, Tadahiro Iimura
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Neuropathic pain
Translation
Neuroinflammation
Non-human primate
Online Access:https://doi.org/10.1038/s41598-025-96160-x
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