MODERN LAXATIVE MEDICATIONS IN PEDIATRIC PRACTICE

The most usable medications in pediatric practice are laxative medicaments on the basis of polyethylene glycol (Macrogol 4000) and lactulose. Macrogol 4000 (Forlax) and lactulose have rela tively equal activity, but the first one has more predictable effect (has linear dependence dose–effect), has a...

Full description

Saved in:
Bibliographic Details
Main Authors: T.V. Gasilina, S.V. Bel'mer
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2008-10-01
Series:Вопросы современной педиатрии
Online Access:https://vsp.spr-journal.ru/jour/article/view/1469
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849242289309745152
author T.V. Gasilina
S.V. Bel'mer
author_facet T.V. Gasilina
S.V. Bel'mer
author_sort T.V. Gasilina
collection DOAJ
description The most usable medications in pediatric practice are laxative medicaments on the basis of polyethylene glycol (Macrogol 4000) and lactulose. Macrogol 4000 (Forlax) and lactulose have rela tively equal activity, but the first one has more predictable effect (has linear dependence dose–effect), has a beneficial activity in the presence of pain syndrome and mucoprotective activity, stimulates appetite. Significant feature of lactulose is its prebiotic activity, and this is the reason of indistinctive dose–effect dependence, presence of latency time and some adverse events; the rate of last ones is low. Authors make a conclusion that the specialist can make a choice of medication, paying attention to peculiarities of disease in every single patient.Key words: children, laxative medicaments, Macrogol 4000.
format Article
id doaj-art-946da85535ed4e0fbf7442318c687fb9
institution Kabale University
issn 1682-5527
1682-5535
language English
publishDate 2008-10-01
publisher "Paediatrician" Publishers LLC
record_format Article
series Вопросы современной педиатрии
spelling doaj-art-946da85535ed4e0fbf7442318c687fb92025-08-20T03:59:52Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352008-10-01751211241469MODERN LAXATIVE MEDICATIONS IN PEDIATRIC PRACTICET.V. Gasilina0S.V. Bel'mer1Russian State Medical University, MoscowRussian State Medical University, MoscowThe most usable medications in pediatric practice are laxative medicaments on the basis of polyethylene glycol (Macrogol 4000) and lactulose. Macrogol 4000 (Forlax) and lactulose have rela tively equal activity, but the first one has more predictable effect (has linear dependence dose–effect), has a beneficial activity in the presence of pain syndrome and mucoprotective activity, stimulates appetite. Significant feature of lactulose is its prebiotic activity, and this is the reason of indistinctive dose–effect dependence, presence of latency time and some adverse events; the rate of last ones is low. Authors make a conclusion that the specialist can make a choice of medication, paying attention to peculiarities of disease in every single patient.Key words: children, laxative medicaments, Macrogol 4000.https://vsp.spr-journal.ru/jour/article/view/1469
spellingShingle T.V. Gasilina
S.V. Bel'mer
MODERN LAXATIVE MEDICATIONS IN PEDIATRIC PRACTICE
Вопросы современной педиатрии
title MODERN LAXATIVE MEDICATIONS IN PEDIATRIC PRACTICE
title_full MODERN LAXATIVE MEDICATIONS IN PEDIATRIC PRACTICE
title_fullStr MODERN LAXATIVE MEDICATIONS IN PEDIATRIC PRACTICE
title_full_unstemmed MODERN LAXATIVE MEDICATIONS IN PEDIATRIC PRACTICE
title_short MODERN LAXATIVE MEDICATIONS IN PEDIATRIC PRACTICE
title_sort modern laxative medications in pediatric practice
url https://vsp.spr-journal.ru/jour/article/view/1469
work_keys_str_mv AT tvgasilina modernlaxativemedicationsinpediatricpractice
AT svbelmer modernlaxativemedicationsinpediatricpractice