Functional activity and connectivity signatures of ketamine and lamotrigine during negative emotional processing: a double-blind randomized controlled fMRI study

Functional activity and connectivity signatures of ketamine and lamotrigine during negative emotional processing: a double-blind randomized controlled fMRI study

Abstract Ketamine is a highly effective antidepressant (AD) that targets the glutamatergic system and exerts profound effects on brain circuits during negative emotional processing. Interestingly, the effects of ketamine on brain measures are sensitive to modulation by pretreatment with lamotrigine,...

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Bibliographic Details
Main Authors: Marvin S. Meiering, David Weigner, Matti Gärtner, Luisa Carstens, Christian Keicher, Rita Hertrampf, Christian F. Beckmann, Maarten Mennes, Andreas Wunder, Anne Weigand, Simone Grimm
Format: Article
Language:English
Published: Nature Publishing Group 2024-10-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-03120-6
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