Mitigation of Methotrexate-Induced Intestinal Mucositis in Male Wistar Rats by Gallic Acid: The Role of HGF and C-Met Genes
Conclusion: GA could increase HGF and C-met expression, decrease inflammatory cytokines, and improve histological injuries, affected by MTX, indicating a beneficial role for GA following GI-M.
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Journal of Toxicology |
| Online Access: | http://dx.doi.org/10.1155/jt/9990692 |
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| _version_ | 1849392064981106688 |
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| author | Reza Norouzirad Khashayar Zahedi Mohammad Mehdi Behvandi Abbas Moridnia Susan Sabbagh |
| author_facet | Reza Norouzirad Khashayar Zahedi Mohammad Mehdi Behvandi Abbas Moridnia Susan Sabbagh |
| author_sort | Reza Norouzirad |
| collection | DOAJ |
| description | Conclusion: GA could increase HGF and C-met expression, decrease inflammatory cytokines, and improve histological injuries, affected by MTX, indicating a beneficial role for GA following GI-M. |
| format | Article |
| id | doaj-art-9462edae83ec4a1b9068cdafa067db35 |
| institution | Kabale University |
| issn | 1687-8205 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Toxicology |
| spelling | doaj-art-9462edae83ec4a1b9068cdafa067db352025-08-20T03:40:51ZengWileyJournal of Toxicology1687-82052025-01-01202510.1155/jt/9990692Mitigation of Methotrexate-Induced Intestinal Mucositis in Male Wistar Rats by Gallic Acid: The Role of HGF and C-Met GenesReza Norouzirad0Khashayar Zahedi1Mohammad Mehdi Behvandi2Abbas Moridnia3Susan Sabbagh4Department of BiochemistryStudent Research CommitteeStudent Research CommitteeDepartment of Genetics and Molecular MedicineDepartment of Anatomical ScienceConclusion: GA could increase HGF and C-met expression, decrease inflammatory cytokines, and improve histological injuries, affected by MTX, indicating a beneficial role for GA following GI-M.http://dx.doi.org/10.1155/jt/9990692 |
| spellingShingle | Reza Norouzirad Khashayar Zahedi Mohammad Mehdi Behvandi Abbas Moridnia Susan Sabbagh Mitigation of Methotrexate-Induced Intestinal Mucositis in Male Wistar Rats by Gallic Acid: The Role of HGF and C-Met Genes Journal of Toxicology |
| title | Mitigation of Methotrexate-Induced Intestinal Mucositis in Male Wistar Rats by Gallic Acid: The Role of HGF and C-Met Genes |
| title_full | Mitigation of Methotrexate-Induced Intestinal Mucositis in Male Wistar Rats by Gallic Acid: The Role of HGF and C-Met Genes |
| title_fullStr | Mitigation of Methotrexate-Induced Intestinal Mucositis in Male Wistar Rats by Gallic Acid: The Role of HGF and C-Met Genes |
| title_full_unstemmed | Mitigation of Methotrexate-Induced Intestinal Mucositis in Male Wistar Rats by Gallic Acid: The Role of HGF and C-Met Genes |
| title_short | Mitigation of Methotrexate-Induced Intestinal Mucositis in Male Wistar Rats by Gallic Acid: The Role of HGF and C-Met Genes |
| title_sort | mitigation of methotrexate induced intestinal mucositis in male wistar rats by gallic acid the role of hgf and c met genes |
| url | http://dx.doi.org/10.1155/jt/9990692 |
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