TREATMENT OUTCOMES OF EXTERNAL BEAM RADIOTHERAPY COMBINED WITH HIGH-DOSE-RATE BRACHYTHERAPY IN PATIENTS WITH ESOPHAGEAL CANCER
Between 2008 and 2015, 82 patients with inoperable esophageal cancer were treated with radiation therapy. The patients were divided into 3 groups. Group I consisted of 30 patients, who received external beam radiation therapy (EBRT) in combination with brachytherapy. Group II and group III patients...
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2017-03-01
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| Series: | Сибирский онкологический журнал |
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| Online Access: | https://www.siboncoj.ru/jour/article/view/494 |
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| author | A. A. Lozhkov A. V. Vazhenin T. M. Sharabura K. I. Kulaev K. S. Zuykov I. M. Usupov E. Y. Mozerova O. N. Davidova M. M. Pimenova K. N. Siroleva A. U. Maksimovskaya |
| author_facet | A. A. Lozhkov A. V. Vazhenin T. M. Sharabura K. I. Kulaev K. S. Zuykov I. M. Usupov E. Y. Mozerova O. N. Davidova M. M. Pimenova K. N. Siroleva A. U. Maksimovskaya |
| author_sort | A. A. Lozhkov |
| collection | DOAJ |
| description | Between 2008 and 2015, 82 patients with inoperable esophageal cancer were treated with radiation therapy. The patients were divided into 3 groups. Group I consisted of 30 patients, who received external beam radiation therapy (EBRT) in combination with brachytherapy. Group II and group III patients (30 and 22 patients, respectively) received EBRT alone. Patients of group II received EBRT at a total dose of 60–70 Gy and patients of group III received EBRT at a total dose of 40–50 Gy. Treatment outcomes were better in patients treated with combination of EBRT and brachytherapy than in patients treated with EBRT alone. There was no significant difference between groups 2 and 3 with regard to their survival rates. Two-year overall survival rates in group I, II and III were 36 %, 12 % and 12 % and the median overall survival time was 15.7; 9.7 and 6.6 months, respectively. |
| format | Article |
| id | doaj-art-945a7239c53042e8b3e18bae3cf840b5 |
| institution | DOAJ |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| publishDate | 2017-03-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj-art-945a7239c53042e8b3e18bae3cf840b52025-08-20T03:18:26ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682017-03-01161717510.21294/1814-4861-2017-16-1-71-75420TREATMENT OUTCOMES OF EXTERNAL BEAM RADIOTHERAPY COMBINED WITH HIGH-DOSE-RATE BRACHYTHERAPY IN PATIENTS WITH ESOPHAGEAL CANCERA. A. Lozhkov0A. V. Vazhenin1T. M. Sharabura2K. I. Kulaev3K. S. Zuykov4I. M. Usupov5E. Y. Mozerova6O. N. Davidova7M. M. Pimenova8K. N. Siroleva9A. U. Maksimovskaya10Chelyabinsk Regional Clinical Oncology Center, ChelyabinskChelyabinsk Regional Clinical Oncology Center, Chelyabinsk South Ural State Medical University, ChelyabinskChelyabinsk Regional Clinical Oncology Center, Chelyabinsk South Ural State Medical University, ChelyabinskChelyabinsk Regional Clinical Oncology Center, Chelyabinsk South Ural State Medical University, ChelyabinskChelyabinsk Regional Clinical Oncology Center, ChelyabinskChelyabinsk Regional Clinical Oncology Center, ChelyabinskChelyabinsk Regional Clinical Oncology Center, Chelyabinsk South Ural State Medical University, ChelyabinskChelyabinsk Regional Clinical Oncology Center, ChelyabinskChelyabinsk Regional Clinical Oncology Center, Chelyabinsk South Ural State Medical University, ChelyabinskChelyabinsk Regional Clinical Oncology Center, ChelyabinskChelyabinsk Regional Clinical Oncology Center, ChelyabinskBetween 2008 and 2015, 82 patients with inoperable esophageal cancer were treated with radiation therapy. The patients were divided into 3 groups. Group I consisted of 30 patients, who received external beam radiation therapy (EBRT) in combination with brachytherapy. Group II and group III patients (30 and 22 patients, respectively) received EBRT alone. Patients of group II received EBRT at a total dose of 60–70 Gy and patients of group III received EBRT at a total dose of 40–50 Gy. Treatment outcomes were better in patients treated with combination of EBRT and brachytherapy than in patients treated with EBRT alone. There was no significant difference between groups 2 and 3 with regard to their survival rates. Two-year overall survival rates in group I, II and III were 36 %, 12 % and 12 % and the median overall survival time was 15.7; 9.7 and 6.6 months, respectively.https://www.siboncoj.ru/jour/article/view/494esophageal cancerbrachytherapyradiation therapy |
| spellingShingle | A. A. Lozhkov A. V. Vazhenin T. M. Sharabura K. I. Kulaev K. S. Zuykov I. M. Usupov E. Y. Mozerova O. N. Davidova M. M. Pimenova K. N. Siroleva A. U. Maksimovskaya TREATMENT OUTCOMES OF EXTERNAL BEAM RADIOTHERAPY COMBINED WITH HIGH-DOSE-RATE BRACHYTHERAPY IN PATIENTS WITH ESOPHAGEAL CANCER Сибирский онкологический журнал esophageal cancer brachytherapy radiation therapy |
| title | TREATMENT OUTCOMES OF EXTERNAL BEAM RADIOTHERAPY COMBINED WITH HIGH-DOSE-RATE BRACHYTHERAPY IN PATIENTS WITH ESOPHAGEAL CANCER |
| title_full | TREATMENT OUTCOMES OF EXTERNAL BEAM RADIOTHERAPY COMBINED WITH HIGH-DOSE-RATE BRACHYTHERAPY IN PATIENTS WITH ESOPHAGEAL CANCER |
| title_fullStr | TREATMENT OUTCOMES OF EXTERNAL BEAM RADIOTHERAPY COMBINED WITH HIGH-DOSE-RATE BRACHYTHERAPY IN PATIENTS WITH ESOPHAGEAL CANCER |
| title_full_unstemmed | TREATMENT OUTCOMES OF EXTERNAL BEAM RADIOTHERAPY COMBINED WITH HIGH-DOSE-RATE BRACHYTHERAPY IN PATIENTS WITH ESOPHAGEAL CANCER |
| title_short | TREATMENT OUTCOMES OF EXTERNAL BEAM RADIOTHERAPY COMBINED WITH HIGH-DOSE-RATE BRACHYTHERAPY IN PATIENTS WITH ESOPHAGEAL CANCER |
| title_sort | treatment outcomes of external beam radiotherapy combined with high dose rate brachytherapy in patients with esophageal cancer |
| topic | esophageal cancer brachytherapy radiation therapy |
| url | https://www.siboncoj.ru/jour/article/view/494 |
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