Liver metastasis from rectal neuroendocrine neoplasm detected 15 years after primary resection

Abstract Background Rectal neuroendocrine neoplasms can induce liver metastasis. However, few reports exist on the associated long-term recurrence rates. We report a case of liver metastasis identified 15 years after rectal neuroendocrine neoplasm resection. Case presentation A 50-year-old woman was...

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Main Authors: Miho Akabane, Satoshi Okubo, Keiichi Kinowaki, Masaru Matsumura, Junichi Shindoh, Masaji Hashimoto
Format: Article
Language:English
Published: Japan Surgical Society 2022-12-01
Series:Surgical Case Reports
Subjects:
Online Access:https://doi.org/10.1186/s40792-022-01569-5
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author Miho Akabane
Satoshi Okubo
Keiichi Kinowaki
Masaru Matsumura
Junichi Shindoh
Masaji Hashimoto
author_facet Miho Akabane
Satoshi Okubo
Keiichi Kinowaki
Masaru Matsumura
Junichi Shindoh
Masaji Hashimoto
author_sort Miho Akabane
collection DOAJ
description Abstract Background Rectal neuroendocrine neoplasms can induce liver metastasis. However, few reports exist on the associated long-term recurrence rates. We report a case of liver metastasis identified 15 years after rectal neuroendocrine neoplasm resection. Case presentation A 50-year-old woman was on semi-annual follow-up after undergoing mastectomy for breast cancer (pT1N0M0) and low anterior resection for grade 1 rectal neuroendocrine neoplasm (pT1b, ly1, v1). Fifteen years postoperatively, a 7-mm hyperechoic mass was identified at liver segment 6. Magnetic resonance imaging revealed a slight growth of the mass. Positron emission tomography/computed tomography revealed radiotracer accumulation in the lesion. Laparoscopic hepatectomy was performed. The histopathological diagnosis was grade 2 neuroendocrine neoplasm. The pathological findings and clinical course indicated the tumor originated in the rectum. Conclusions Our findings highlight the need to reassess the optimal postoperative follow-up period for patients with rectal neuroendocrine neoplasm.
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institution Kabale University
issn 2198-7793
language English
publishDate 2022-12-01
publisher Japan Surgical Society
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series Surgical Case Reports
spelling doaj-art-945a4f16a6964d0d9c4bafdd939f43b62025-08-20T03:34:52ZengJapan Surgical SocietySurgical Case Reports2198-77932022-12-01811510.1186/s40792-022-01569-5Liver metastasis from rectal neuroendocrine neoplasm detected 15 years after primary resectionMiho Akabane0Satoshi Okubo1Keiichi Kinowaki2Masaru Matsumura3Junichi Shindoh4Masaji Hashimoto5Hepatobiliary-Pancreatic Surgery Division, Department of Gastroenterological Surgery, Toranomon HospitalHepatobiliary-Pancreatic Surgery Division, Department of Gastroenterological Surgery, Toranomon HospitalDepartment of Pathology, Toranomon HospitalHepatobiliary-Pancreatic Surgery Division, Department of Gastroenterological Surgery, Toranomon HospitalHepatobiliary-Pancreatic Surgery Division, Department of Gastroenterological Surgery, Toranomon HospitalHepatobiliary-Pancreatic Surgery Division, Department of Gastroenterological Surgery, Toranomon HospitalAbstract Background Rectal neuroendocrine neoplasms can induce liver metastasis. However, few reports exist on the associated long-term recurrence rates. We report a case of liver metastasis identified 15 years after rectal neuroendocrine neoplasm resection. Case presentation A 50-year-old woman was on semi-annual follow-up after undergoing mastectomy for breast cancer (pT1N0M0) and low anterior resection for grade 1 rectal neuroendocrine neoplasm (pT1b, ly1, v1). Fifteen years postoperatively, a 7-mm hyperechoic mass was identified at liver segment 6. Magnetic resonance imaging revealed a slight growth of the mass. Positron emission tomography/computed tomography revealed radiotracer accumulation in the lesion. Laparoscopic hepatectomy was performed. The histopathological diagnosis was grade 2 neuroendocrine neoplasm. The pathological findings and clinical course indicated the tumor originated in the rectum. Conclusions Our findings highlight the need to reassess the optimal postoperative follow-up period for patients with rectal neuroendocrine neoplasm.https://doi.org/10.1186/s40792-022-01569-5Neoplasm metastasisNeuroendocrine tumorsRectal neoplasms
spellingShingle Miho Akabane
Satoshi Okubo
Keiichi Kinowaki
Masaru Matsumura
Junichi Shindoh
Masaji Hashimoto
Liver metastasis from rectal neuroendocrine neoplasm detected 15 years after primary resection
Surgical Case Reports
Neoplasm metastasis
Neuroendocrine tumors
Rectal neoplasms
title Liver metastasis from rectal neuroendocrine neoplasm detected 15 years after primary resection
title_full Liver metastasis from rectal neuroendocrine neoplasm detected 15 years after primary resection
title_fullStr Liver metastasis from rectal neuroendocrine neoplasm detected 15 years after primary resection
title_full_unstemmed Liver metastasis from rectal neuroendocrine neoplasm detected 15 years after primary resection
title_short Liver metastasis from rectal neuroendocrine neoplasm detected 15 years after primary resection
title_sort liver metastasis from rectal neuroendocrine neoplasm detected 15 years after primary resection
topic Neoplasm metastasis
Neuroendocrine tumors
Rectal neoplasms
url https://doi.org/10.1186/s40792-022-01569-5
work_keys_str_mv AT mihoakabane livermetastasisfromrectalneuroendocrineneoplasmdetected15yearsafterprimaryresection
AT satoshiokubo livermetastasisfromrectalneuroendocrineneoplasmdetected15yearsafterprimaryresection
AT keiichikinowaki livermetastasisfromrectalneuroendocrineneoplasmdetected15yearsafterprimaryresection
AT masarumatsumura livermetastasisfromrectalneuroendocrineneoplasmdetected15yearsafterprimaryresection
AT junichishindoh livermetastasisfromrectalneuroendocrineneoplasmdetected15yearsafterprimaryresection
AT masajihashimoto livermetastasisfromrectalneuroendocrineneoplasmdetected15yearsafterprimaryresection