Immunomodulatory effects of apical papilla cells on periodontal ligament fibroblasts stimulated with Escherichia coli lipopolysaccharide: an in vitro study

Abstract The role of human Stem Cells from the Apical Papilla (SCAP) in tissue regeneration has been described, but their impact on modulating the apical inflammatory process by other surrounding cell populations, such as periodontal ligament fibroblasts (PLFs), is unclear. Therefore, we investigate...

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Bibliographic Details
Main Authors: Alexandre Guimarães dos SANTOS, Karollyne Santos SPIGARIOL, Letícia Martins SANTOS, Marinella HOLZHAUSEN, Carla Renata SIPERT
Format: Article
Language:English
Published: University of São Paulo 2025-03-01
Series:Journal of Applied Oral Science
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572025000100409&lng=en&tlng=en
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