Influence of plasma processing on recovery and analysis of circulating nucleic acids.

Influence of plasma processing on recovery and analysis of circulating nucleic acids.

Circulating nucleic acids (CNAs) are under investigation as a liquid biopsy in cancer. However there is wide variation in blood processing and methods for isolation of circulating free DNA (cfDNA) and microRNAs (miRNAs). Here we compare the extraction efficiency and reproducibility of 4 commercially...

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Main Authors: Karen Page, David S Guttery, Nathalie Zahra, Lindsay Primrose, Shona R Elshaw, J Howard Pringle, Kevin Blighe, Stephanie D Marchese, Allison Hills, Laura Woodley, Justin Stebbing, R Charles Coombes, Jacqueline A Shaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0077963&type=printable
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