FUNCTIONAL ACTIVITY OF IFNα- AND IL-4-INDUCED HUMAN DENDRITIC CELLS: A COMPARATIVE STUDY

FUNCTIONAL ACTIVITY OF IFNα- AND IL-4-INDUCED HUMAN DENDRITIC CELLS: A COMPARATIVE STUDY

We have performed a comparative analysis of allostimulatory, Th1/Th2-stimulatory andtolerogenic activities of dendritic cells (DCs) derived from healthy donors (n = 52). The DCs were generatedin vitro with IFN-alpha (IFN-DCs) or IL-4 (IL-4-DCs). It was shown that IL-4-DCs and IFN-DCs didnot differ i...

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Bibliographic Details
Main Authors: O. Yu. Leplina, M. A. Tikhonova, T. V. Tyrinova, E. A. Alyamkina, S. S. Bogachev, A. A, Ostanin, E. R. Chernykh
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:Медицинская иммунология
Subjects:
dendritic cells
allostimulatory activity
th1-/th2-сytokines
regulatory t-cells
Online Access:https://www.mimmun.ru/mimmun/article/view/22
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