Clinical and radiologic outcomes of dental implants in cemento-osseous dysplasia: a systematic review and retrospective case series

Abstract Objectives To systematically evaluate the clinical and radiologic outcomes of dental implants in cementoosseous dysplasia (COD)-affected regions, identify factors associated with implant success or failure, and propose evidence-based management recommendations. Materials and methods EMBASE...

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Main Authors: Hongying Hu, Li Liu, Yi Man, Zelin Ye, Meng You
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Oral Health
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Online Access:https://doi.org/10.1186/s12903-025-06509-x
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author Hongying Hu
Li Liu
Yi Man
Zelin Ye
Meng You
author_facet Hongying Hu
Li Liu
Yi Man
Zelin Ye
Meng You
author_sort Hongying Hu
collection DOAJ
description Abstract Objectives To systematically evaluate the clinical and radiologic outcomes of dental implants in cementoosseous dysplasia (COD)-affected regions, identify factors associated with implant success or failure, and propose evidence-based management recommendations. Materials and methods EMBASE (Ovid), PubMed, Scopus, CNKI, and SinoMed databases were searched for eligible studies (up to March 2025). Studies reporting dental implants placed in COD-affected regions with ≥ three months’ follow-up were included. Risk of bias was assessed using the JBI critical appraisal checklist for case reports. To complement the systematic review, retrospective institutional cases were included. Pooled analysis examined associations between implant outcomes and COD type, lesion stage, and implant-to-lesion spatial relationship. Results Seventeen implants from eleven published studies and twelve implants from six institutional cases were analyzed (N = 29). The overall implant success rate was 79.3% (median follow-up: 25 months). All failures occurred in florid COD (FLCOD); focal COD (FCOD) cases achieved 100% success. Stage III lesions showed higher success (87.5%) than stage II lesions (40%). Implants with no or minimal lesion contact had 100% success, while those embedded in lesions had a 46.15% failure rate. Conclusion Dental implants demonstrated high success rates in FCOD and Stage III COD lesions, particularly when direct embedding within the dysplastic bone was avoided, underscoring the importance of careful case selection, strategic implant positioning, and rigorous postoperative management. Clinical trial number Not applicable.
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spelling doaj-art-9447290b684949dd8f6780a304ef0bba2025-08-20T04:01:42ZengBMCBMC Oral Health1472-68312025-07-012511910.1186/s12903-025-06509-xClinical and radiologic outcomes of dental implants in cemento-osseous dysplasia: a systematic review and retrospective case seriesHongying Hu0Li Liu1Yi Man2Zelin Ye3Meng You4State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral Medical Imaging, West China Hospital of Stomatology, Sichuan UniversityState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral Medical Imaging, West China Hospital of Stomatology, Sichuan UniversityState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral Implantology, West China Hospital of Stomatology, Sichuan UniversityFaculty of Dentistry, The University of Hong KongState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral Medical Imaging, West China Hospital of Stomatology, Sichuan UniversityAbstract Objectives To systematically evaluate the clinical and radiologic outcomes of dental implants in cementoosseous dysplasia (COD)-affected regions, identify factors associated with implant success or failure, and propose evidence-based management recommendations. Materials and methods EMBASE (Ovid), PubMed, Scopus, CNKI, and SinoMed databases were searched for eligible studies (up to March 2025). Studies reporting dental implants placed in COD-affected regions with ≥ three months’ follow-up were included. Risk of bias was assessed using the JBI critical appraisal checklist for case reports. To complement the systematic review, retrospective institutional cases were included. Pooled analysis examined associations between implant outcomes and COD type, lesion stage, and implant-to-lesion spatial relationship. Results Seventeen implants from eleven published studies and twelve implants from six institutional cases were analyzed (N = 29). The overall implant success rate was 79.3% (median follow-up: 25 months). All failures occurred in florid COD (FLCOD); focal COD (FCOD) cases achieved 100% success. Stage III lesions showed higher success (87.5%) than stage II lesions (40%). Implants with no or minimal lesion contact had 100% success, while those embedded in lesions had a 46.15% failure rate. Conclusion Dental implants demonstrated high success rates in FCOD and Stage III COD lesions, particularly when direct embedding within the dysplastic bone was avoided, underscoring the importance of careful case selection, strategic implant positioning, and rigorous postoperative management. Clinical trial number Not applicable.https://doi.org/10.1186/s12903-025-06509-xDental implantCemento-osseous dysplasiaOsseointegrationSystematic review
spellingShingle Hongying Hu
Li Liu
Yi Man
Zelin Ye
Meng You
Clinical and radiologic outcomes of dental implants in cemento-osseous dysplasia: a systematic review and retrospective case series
BMC Oral Health
Dental implant
Cemento-osseous dysplasia
Osseointegration
Systematic review
title Clinical and radiologic outcomes of dental implants in cemento-osseous dysplasia: a systematic review and retrospective case series
title_full Clinical and radiologic outcomes of dental implants in cemento-osseous dysplasia: a systematic review and retrospective case series
title_fullStr Clinical and radiologic outcomes of dental implants in cemento-osseous dysplasia: a systematic review and retrospective case series
title_full_unstemmed Clinical and radiologic outcomes of dental implants in cemento-osseous dysplasia: a systematic review and retrospective case series
title_short Clinical and radiologic outcomes of dental implants in cemento-osseous dysplasia: a systematic review and retrospective case series
title_sort clinical and radiologic outcomes of dental implants in cemento osseous dysplasia a systematic review and retrospective case series
topic Dental implant
Cemento-osseous dysplasia
Osseointegration
Systematic review
url https://doi.org/10.1186/s12903-025-06509-x
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