Complications after radiofrequency ablation of hyperparathyroidism secondary to chronic kidney disease
Objective To study the complications of ultrasound-guided radiofrequency ablation (RFA) in chronic kidney disease (CKD) patients undergoing renal replacement therapy with secondary hyperparathyroidism (SHPT).Methods This retrospective study reviewed the clinical data, including general information,...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Renal Failure |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2023.2215334 |
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| author | Li-Ping Lin Miao Lin Song-Song Wu Wei-hua Liu Li Zhang Yi-ping Ruan Mei-zhu Gao Fu-Yuan Hong |
| author_facet | Li-Ping Lin Miao Lin Song-Song Wu Wei-hua Liu Li Zhang Yi-ping Ruan Mei-zhu Gao Fu-Yuan Hong |
| author_sort | Li-Ping Lin |
| collection | DOAJ |
| description | Objective To study the complications of ultrasound-guided radiofrequency ablation (RFA) in chronic kidney disease (CKD) patients undergoing renal replacement therapy with secondary hyperparathyroidism (SHPT).Methods This retrospective study reviewed the clinical data, including general information, examination results, treatment times, time interval, and postoperative complications, of 103 SHPT patients who received ultrasound-guided RFA treatment from July 2017 to January 2021.Results Of 103 patients, 52 required two sessions of RFA within a month. The incidence of recurrent laryngeal nerve injury at the second treatment was significantly higher than that at the first treatment (first session vs. second session, 5.77% vs. 21.15%; p = .021). Of all the enrolled 103 patients, 27 suffered complications after the first session of RFA. When we separated patients into complications group and non-complication group, we detected more ablated nodules in the complications group (Z = −2.222; p = .0026). Subgroup analysis further showed that the patients in the severe hypocalcemia group were younger (p = .005), had more ablated nodules (p = .003) and higher blood phosphorus (p = .012) and alkaline phosphatase (ALP) levels (p = .002). Univariate analysis showed that age, serum phosphorus, ALP, and number of ablated nodules were associated with a higher risk of severe hypocalcemia after the first session of RFA.Conclusions An interval of more than 1 month between two treatments may help to avoid recurrent laryngeal nerve injury. Age, serum phosphorus, ALP, and number of ablated nodules were associated with a higher risk of severe hypocalcemia after the first session of RFA. |
| format | Article |
| id | doaj-art-94411cd002604e27b1ef6c91b3decd4c |
| institution | DOAJ |
| issn | 0886-022X 1525-6049 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Renal Failure |
| spelling | doaj-art-94411cd002604e27b1ef6c91b3decd4c2025-08-20T02:56:09ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492023-12-0145110.1080/0886022X.2023.2215334Complications after radiofrequency ablation of hyperparathyroidism secondary to chronic kidney diseaseLi-Ping Lin0Miao Lin1Song-Song Wu2Wei-hua Liu3Li Zhang4Yi-ping Ruan5Mei-zhu Gao6Fu-Yuan Hong7Department of Nephrology, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of ChinaDepartment of Nephrology, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of ChinaDepartment of Ultrasonography, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of ChinaDepartment of Nephrology, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of ChinaDepartment of Nephrology, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of ChinaDepartment of Nephrology, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of ChinaDepartment of Nephrology, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of ChinaDepartment of Nephrology, Shengli Clinical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People’s Republic of ChinaObjective To study the complications of ultrasound-guided radiofrequency ablation (RFA) in chronic kidney disease (CKD) patients undergoing renal replacement therapy with secondary hyperparathyroidism (SHPT).Methods This retrospective study reviewed the clinical data, including general information, examination results, treatment times, time interval, and postoperative complications, of 103 SHPT patients who received ultrasound-guided RFA treatment from July 2017 to January 2021.Results Of 103 patients, 52 required two sessions of RFA within a month. The incidence of recurrent laryngeal nerve injury at the second treatment was significantly higher than that at the first treatment (first session vs. second session, 5.77% vs. 21.15%; p = .021). Of all the enrolled 103 patients, 27 suffered complications after the first session of RFA. When we separated patients into complications group and non-complication group, we detected more ablated nodules in the complications group (Z = −2.222; p = .0026). Subgroup analysis further showed that the patients in the severe hypocalcemia group were younger (p = .005), had more ablated nodules (p = .003) and higher blood phosphorus (p = .012) and alkaline phosphatase (ALP) levels (p = .002). Univariate analysis showed that age, serum phosphorus, ALP, and number of ablated nodules were associated with a higher risk of severe hypocalcemia after the first session of RFA.Conclusions An interval of more than 1 month between two treatments may help to avoid recurrent laryngeal nerve injury. Age, serum phosphorus, ALP, and number of ablated nodules were associated with a higher risk of severe hypocalcemia after the first session of RFA.https://www.tandfonline.com/doi/10.1080/0886022X.2023.2215334Chronic kidney diseasessecondary hyperparathyroidismradiofrequency ablationcomplicationsrecurrent laryngeal nerve injurysevere hypocalcemia |
| spellingShingle | Li-Ping Lin Miao Lin Song-Song Wu Wei-hua Liu Li Zhang Yi-ping Ruan Mei-zhu Gao Fu-Yuan Hong Complications after radiofrequency ablation of hyperparathyroidism secondary to chronic kidney disease Renal Failure Chronic kidney diseases secondary hyperparathyroidism radiofrequency ablation complications recurrent laryngeal nerve injury severe hypocalcemia |
| title | Complications after radiofrequency ablation of hyperparathyroidism secondary to chronic kidney disease |
| title_full | Complications after radiofrequency ablation of hyperparathyroidism secondary to chronic kidney disease |
| title_fullStr | Complications after radiofrequency ablation of hyperparathyroidism secondary to chronic kidney disease |
| title_full_unstemmed | Complications after radiofrequency ablation of hyperparathyroidism secondary to chronic kidney disease |
| title_short | Complications after radiofrequency ablation of hyperparathyroidism secondary to chronic kidney disease |
| title_sort | complications after radiofrequency ablation of hyperparathyroidism secondary to chronic kidney disease |
| topic | Chronic kidney diseases secondary hyperparathyroidism radiofrequency ablation complications recurrent laryngeal nerve injury severe hypocalcemia |
| url | https://www.tandfonline.com/doi/10.1080/0886022X.2023.2215334 |
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