Exploring the Therapeutic Effect of Ficus benghalensis Fruit Powder against Diabetes in Albino Rats

Diabetes is a chronic metabolic disease. International diabetic federation (IDF) reported that approximately about 8 million people died of diabetes in 2021. This highlights the widespread nature of diabetes, a prevalent non-communicable disease characterized by high blood glucose level. Interesting...

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Main Authors: Ali Usman, Muhammad Kashif Iqbal Khan, Ali Hassan, Sabiha Abbas, Hafiz Nafees Ul Hassan, Samia Fiaz, Qirat Aslam, Hifza Saher, Sonia
Format: Article
Language:English
Published: EcoScribe Publishers Company Limited 2025-05-01
Series:Journal of Food Innovation, Nutrition, and Environmental Sciences
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Online Access:https://jfines.org/index.php/jfines/article/view/30
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author Ali Usman
Muhammad Kashif Iqbal Khan
Ali Hassan
Sabiha Abbas
Hafiz Nafees Ul Hassan
Samia Fiaz
Qirat Aslam
Hifza Saher
Sonia
author_facet Ali Usman
Muhammad Kashif Iqbal Khan
Ali Hassan
Sabiha Abbas
Hafiz Nafees Ul Hassan
Samia Fiaz
Qirat Aslam
Hifza Saher
Sonia
author_sort Ali Usman
collection DOAJ
description Diabetes is a chronic metabolic disease. International diabetic federation (IDF) reported that approximately about 8 million people died of diabetes in 2021. This highlights the widespread nature of diabetes, a prevalent non-communicable disease characterized by high blood glucose level. Interestingly, within the realm of traditional medicine particularly ayurveda, the Ficus benghalensis (commonly known as Banyan fruit) boasts a long history of medicinal applications primarily the bark, fruit, and aerial roots of this plant are used to treat diabetes. Banyan fruit contains many bioactive compounds such as glycosides and polyphenols that help the body in the regulation of diabetes. In this study, the fruit was dried by different methods such as hot air method, microwave oven drying, and sun drying. The dried fruit was stored for further usage. The effect of drying treatment on the Ficus benghalensis fruit was assessed through proximate analysis, phytochemical profile, total saponin contents, and vitamin C contents present in it. The anti-diabetic potential of the fruit powder was assessed in albino rats. The sample dried through the sun drying showed the best results of moisture, fat, protein, and other proximate values. The value of total phenolic contents (TPC) and antioxidant capacity (DPPH) was highest in the microwave oven dried, while total flavonoid contents (TFC) were highest in the hot air oven-dried sample. The amount of vitamin C contents was also highest in microwave oven dried sample. Then the anti-diabetic effect of the powder at 500mg/kg body showed the best results while the 250mg/kg and 350mg/kg showed less effect against diabetes.
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publisher EcoScribe Publishers Company Limited
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spelling doaj-art-943b7af4cb4c4ec8bd1be4763186ddcc2025-08-20T03:14:08ZengEcoScribe Publishers Company LimitedJournal of Food Innovation, Nutrition, and Environmental Sciences3078-55372025-05-0122354510.70851/jfines.2025.2(2).35.4578Exploring the Therapeutic Effect of Ficus benghalensis Fruit Powder against Diabetes in Albino RatsAli Usman0https://orcid.org/0009-0000-3075-2455Muhammad Kashif Iqbal Khan1Ali Hassan2Sabiha Abbas3Hafiz Nafees Ul Hassan4Samia Fiaz5Qirat Aslam6Hifza Saher7Sonia8National Institute of Food Science and Technology, University of Agriculture Faisalabad 38000, PakistanNational Institute of Food Science and Technology, University of Agriculture Faisalabad 38000, PakistanNational Institute of Food Science and Technology, University of Agriculture Faisalabad 38000, PakistanRiphah International University Sahiwal CampusNational Institute of Food Science and Technology, University of Agriculture Faisalabad 38000, PakistanGovernment College University FaisalabadNational Institute of Food Science and Technology, University of Agriculture Faisalabad 38000, PakistanGovernment College University, FaisalabadNational Institute of Food Science and Technology, University of Agriculture Faisalabad 38000, PakistanDiabetes is a chronic metabolic disease. International diabetic federation (IDF) reported that approximately about 8 million people died of diabetes in 2021. This highlights the widespread nature of diabetes, a prevalent non-communicable disease characterized by high blood glucose level. Interestingly, within the realm of traditional medicine particularly ayurveda, the Ficus benghalensis (commonly known as Banyan fruit) boasts a long history of medicinal applications primarily the bark, fruit, and aerial roots of this plant are used to treat diabetes. Banyan fruit contains many bioactive compounds such as glycosides and polyphenols that help the body in the regulation of diabetes. In this study, the fruit was dried by different methods such as hot air method, microwave oven drying, and sun drying. The dried fruit was stored for further usage. The effect of drying treatment on the Ficus benghalensis fruit was assessed through proximate analysis, phytochemical profile, total saponin contents, and vitamin C contents present in it. The anti-diabetic potential of the fruit powder was assessed in albino rats. The sample dried through the sun drying showed the best results of moisture, fat, protein, and other proximate values. The value of total phenolic contents (TPC) and antioxidant capacity (DPPH) was highest in the microwave oven dried, while total flavonoid contents (TFC) were highest in the hot air oven-dried sample. The amount of vitamin C contents was also highest in microwave oven dried sample. Then the anti-diabetic effect of the powder at 500mg/kg body showed the best results while the 250mg/kg and 350mg/kg showed less effect against diabetes.https://jfines.org/index.php/jfines/article/view/30banyan fruitdiabetes ayurvedanutraceuticals
spellingShingle Ali Usman
Muhammad Kashif Iqbal Khan
Ali Hassan
Sabiha Abbas
Hafiz Nafees Ul Hassan
Samia Fiaz
Qirat Aslam
Hifza Saher
Sonia
Exploring the Therapeutic Effect of Ficus benghalensis Fruit Powder against Diabetes in Albino Rats
Journal of Food Innovation, Nutrition, and Environmental Sciences
banyan fruit
diabetes
ayurveda
nutraceuticals
title Exploring the Therapeutic Effect of Ficus benghalensis Fruit Powder against Diabetes in Albino Rats
title_full Exploring the Therapeutic Effect of Ficus benghalensis Fruit Powder against Diabetes in Albino Rats
title_fullStr Exploring the Therapeutic Effect of Ficus benghalensis Fruit Powder against Diabetes in Albino Rats
title_full_unstemmed Exploring the Therapeutic Effect of Ficus benghalensis Fruit Powder against Diabetes in Albino Rats
title_short Exploring the Therapeutic Effect of Ficus benghalensis Fruit Powder against Diabetes in Albino Rats
title_sort exploring the therapeutic effect of ficus benghalensis fruit powder against diabetes in albino rats
topic banyan fruit
diabetes
ayurveda
nutraceuticals
url https://jfines.org/index.php/jfines/article/view/30
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