Development of rematuration of canine chemically induced hepatic progenitor cells using 3D rocking culture

Development of rematuration of canine chemically induced hepatic progenitor cells using 3D rocking culture

Introduction: Developing canine hepatocyte culture systems is critical for liver transplantation, toxicity evaluation, and drug metabolism studies. However, maintaining viable and functional hepatocytes in long-term cultures remains challenging. Our prior research demonstrated differentiation of cry...

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Bibliographic Details
Main Authors: Kaoruko Kikuchi, Yoko Yamada, Sakurako Neo, Suguru Nitta, Hirotaka Igarashi, Akihide Kamiya, Masaharu Hisasue
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Regenerative Therapy
Subjects:
Canine hepatic progenitor cells
Liver spheroids
3D culture
Hepatocyte maturation
In vitro liver model
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320425001361
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