Research progress on the synthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone by microorganisms

4-hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF) is a safe and excellent sweet flavor and aroma agent with caramel taste, which has a lower threshold, good fragrance potential, and strong characteristics, which is widely used in food, tobacco, and other products, and the market demand is large, especial...

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Main Author: SONG Jinpeng, ZHONG Xiufang, LI Xuesi, CAO Zhenhua, PENG Xinhui, FAN Guangsen
Format: Article
Language:English
Published: Editorial Department of China Brewing 2024-04-01
Series:Zhongguo niangzao
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Online Access:https://manu61.magtech.com.cn/zgnz/fileup/0254-5071/PDF/0254-5071-2024-43-4-14.pdf
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author SONG Jinpeng, ZHONG Xiufang, LI Xuesi, CAO Zhenhua, PENG Xinhui, FAN Guangsen
author_facet SONG Jinpeng, ZHONG Xiufang, LI Xuesi, CAO Zhenhua, PENG Xinhui, FAN Guangsen
author_sort SONG Jinpeng, ZHONG Xiufang, LI Xuesi, CAO Zhenhua, PENG Xinhui, FAN Guangsen
collection DOAJ
description 4-hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF) is a safe and excellent sweet flavor and aroma agent with caramel taste, which has a lower threshold, good fragrance potential, and strong characteristics, which is widely used in food, tobacco, and other products, and the market demand is large, especially for natural sources of HDMF. However, the yield of natural HDMF is low and cannot meet the current market demand. For this reason, the application, detection, production methods, species of microorganisms that synthesize HDMF, mechanism of microbial synthesis of HDMF, and key enzymes as well as influencing factors of fermentation culture conditions were briefly reviewed. The main focus was on the microorganisms species that have been reported to synthesize HDMF, the internal mechanism of microbial synthesis of HDMF and the culture factors affecting its fermentation, aiming to provide a reference for subsequent screening, modification and obtaining excellent and high-yield HDMF strains, and optimize the microbial fermentation conditions to achieve efficient preparation of natural HDMF by biological methods.
format Article
id doaj-art-942b3f91a9ff4195a129ec603586d53a
institution DOAJ
issn 0254-5071
language English
publishDate 2024-04-01
publisher Editorial Department of China Brewing
record_format Article
series Zhongguo niangzao
spelling doaj-art-942b3f91a9ff4195a129ec603586d53a2025-08-20T02:45:56ZengEditorial Department of China BrewingZhongguo niangzao0254-50712024-04-01434142110.11882/j.issn.0254-5071.2024.04.003Research progress on the synthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone by microorganismsSONG Jinpeng, ZHONG Xiufang, LI Xuesi, CAO Zhenhua, PENG Xinhui, FAN Guangsen01. Dezhou Institute of Fiber Inspection, Dezhou 253000, China; ;2. School of Food and Health, Beijing Technology and Business University, Beijing 100048, China; ;3. College of Food and Biological Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China; ;4. Henan Songhe Distillery Co., Ltd., Luyi 477265, China; ;5. China Tobacco Hunan Industrial Co., Ltd., Changsha 410000, China4-hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF) is a safe and excellent sweet flavor and aroma agent with caramel taste, which has a lower threshold, good fragrance potential, and strong characteristics, which is widely used in food, tobacco, and other products, and the market demand is large, especially for natural sources of HDMF. However, the yield of natural HDMF is low and cannot meet the current market demand. For this reason, the application, detection, production methods, species of microorganisms that synthesize HDMF, mechanism of microbial synthesis of HDMF, and key enzymes as well as influencing factors of fermentation culture conditions were briefly reviewed. The main focus was on the microorganisms species that have been reported to synthesize HDMF, the internal mechanism of microbial synthesis of HDMF and the culture factors affecting its fermentation, aiming to provide a reference for subsequent screening, modification and obtaining excellent and high-yield HDMF strains, and optimize the microbial fermentation conditions to achieve efficient preparation of natural HDMF by biological methods.https://manu61.magtech.com.cn/zgnz/fileup/0254-5071/PDF/0254-5071-2024-43-4-14.pdf4-hydroxy-2|5-dimethyl-3(2h)-furanone|microbial synthesis|synthesis mechanism|culture condition
spellingShingle SONG Jinpeng, ZHONG Xiufang, LI Xuesi, CAO Zhenhua, PENG Xinhui, FAN Guangsen
Research progress on the synthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone by microorganisms
Zhongguo niangzao
4-hydroxy-2|5-dimethyl-3(2h)-furanone|microbial synthesis|synthesis mechanism|culture condition
title Research progress on the synthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone by microorganisms
title_full Research progress on the synthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone by microorganisms
title_fullStr Research progress on the synthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone by microorganisms
title_full_unstemmed Research progress on the synthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone by microorganisms
title_short Research progress on the synthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone by microorganisms
title_sort research progress on the synthesis of 4 hydroxy 2 5 dimethyl 3 2h furanone by microorganisms
topic 4-hydroxy-2|5-dimethyl-3(2h)-furanone|microbial synthesis|synthesis mechanism|culture condition
url https://manu61.magtech.com.cn/zgnz/fileup/0254-5071/PDF/0254-5071-2024-43-4-14.pdf
work_keys_str_mv AT songjinpengzhongxiufanglixuesicaozhenhuapengxinhuifanguangsen researchprogressonthesynthesisof4hydroxy25dimethyl32hfuranonebymicroorganisms