Chitosan-Hyaluronate Hybrid Gel Intraarticular Injection Delays Osteoarthritis Progression and Reduces Pain in a Rat Meniscectomy Model as Compared to Saline and Hyaluronate Treatment

Chitosan-Hyaluronate hybrid gel (CHHG) is a self-forming thermo-responsive hydrogel. The current study was undertaken in order to assess the effect of CHHG on rat's surgically induced osteoarthritis. Methods. Thirteen rats were included in the study. In all rats weight-bearing was assessed usin...

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Bibliographic Details
Main Authors: Shachar Patchornik, Edward Ram, Noah Ben Shalom, Zvi Nevo, Dror Robinson
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Advances in Orthopedics
Online Access:http://dx.doi.org/10.1155/2012/979152
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