Chemical Analysis and Evaluation of Antioxidant, Antimicrobial, and Photoprotective Activities of Schinopsis brasiliensis Engl. (Anacardiaceae)

Schinopsis brasiliensis Engl. is a native plant of Caatinga which has high concentrations of compounds capable of absorbing ultraviolet light, suggesting its potential application for the development of sunscreen preparations. After its identification and collection, this vegetable drug was submitte...

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Main Authors: Sarah Raquel Gomes de Lima-Saraiva, Fernanda Granja da Silva Oliveira, Raimundo Gonçalves de Oliveira Junior, Camila de Souza Araújo, Ana Paula de Oliveira, Alessandra Gomes Marques Pacheco, Larissa Araújo Rolim, Elba Lúcia Cavalcanti de Amorim, Francine Celise Siqueira César, Jackson Roberto Guedes da Silva Almeida
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2017/1713921
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Summary:Schinopsis brasiliensis Engl. is a native plant of Caatinga which has high concentrations of compounds capable of absorbing ultraviolet light, suggesting its potential application for the development of sunscreen preparations. After its identification and collection, this vegetable drug was submitted to a physicochemical analysis through the preparation of ethanolic extract. The phytochemical screening and analysis of extracts were carried out by high-performance liquid chromatography (HPLC) evaluation. The antioxidant activity of the extract was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and β-carotene bleaching test. Inhibitory hemolytic activity and morphological deformation of erythrocytes induced by H2O2 were also demonstrated and the antimicrobial activity was analyzed by the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) method. For the in vitro determination of the sun protection factor (SPF), the spectrophotometric method was used. From the analyses carried out with this species, this plant showed significant results for the antioxidant and antimicrobial activities, as well as sunscreen action. Important flavonoids were identified. These data are an important step for the development of new photoprotective cosmetic with Caatinga species, revealing importance and representing another incentive for the preservation of the species involved and analyzed in the study.
ISSN:2356-6140
1537-744X