COMPLEX ASSESSMENT OF EFFICACY OF STATINS PRESCRIBED AT MOST BY CLINICIANS
Aim. To evaluate a complex clinical efficacy, tolerability and safety of statin drugs — simvastatin, atorvastatin, rosuvastatin in patients with hyperlipidemia (HL).Material and methods. The assessment of clinical efficacy was done in 90 patients with HL and arterial hypertension of the grades 1 and...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2018-06-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/791 |
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| author | A. S. Sivkov E. V. Shih M. A. Osadchuk S. K. Sivkova N. V. Kireeva N. P. Chernus |
| author_facet | A. S. Sivkov E. V. Shih M. A. Osadchuk S. K. Sivkova N. V. Kireeva N. P. Chernus |
| author_sort | A. S. Sivkov |
| collection | DOAJ |
| description | Aim. To evaluate a complex clinical efficacy, tolerability and safety of statin drugs — simvastatin, atorvastatin, rosuvastatin in patients with hyperlipidemia (HL).Material and methods. The assessment of clinical efficacy was done in 90 patients with HL and arterial hypertension of the grades 1 and 2, age 40-75 y.o.; some of them had coronary heart disease.Results. In 90 patients with cardiac pathology and HL, selected to 3 groups by 30 persons, the clinical efficacy of the listed statins was assessed. A significant hypolipidemic effect was noted as a decline of atherogenicity of the blood, with slight more prominent effect of rosuvastatin.Conclusion. The data makes it to conclude the simvastatin, atorvastatin and rosuvastatin are equally effective hypolipidemic drugs in HL type IIA and IIB patients. The time frame, type and grade of positive changes in lipid profile are almost the same, and in rosuvastatin just slightly more prominent. |
| format | Article |
| id | doaj-art-9418df9e5d2a40cbb440252c902373c2 |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2018-06-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-9418df9e5d2a40cbb440252c902373c22025-08-20T03:35:47Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252018-06-01173222610.15829/1728-8800-2018-3-22-26567COMPLEX ASSESSMENT OF EFFICACY OF STATINS PRESCRIBED AT MOST BY CLINICIANSA. S. Sivkov0E. V. Shih1M. A. Osadchuk2S. K. Sivkova3N. V. Kireeva4N. P. Chernus5I. M. Sechenov First Moscow State Medical University of the Ministry of HealthI. M. Sechenov First Moscow State Medical University of the Ministry of HealthI. M. Sechenov First Moscow State Medical University of the Ministry of HealthI. M. Sechenov First Moscow State Medical University of the Ministry of HealthI. M. Sechenov First Moscow State Medical University of the Ministry of HealthI. M. Sechenov First Moscow State Medical University of the Ministry of HealthAim. To evaluate a complex clinical efficacy, tolerability and safety of statin drugs — simvastatin, atorvastatin, rosuvastatin in patients with hyperlipidemia (HL).Material and methods. The assessment of clinical efficacy was done in 90 patients with HL and arterial hypertension of the grades 1 and 2, age 40-75 y.o.; some of them had coronary heart disease.Results. In 90 patients with cardiac pathology and HL, selected to 3 groups by 30 persons, the clinical efficacy of the listed statins was assessed. A significant hypolipidemic effect was noted as a decline of atherogenicity of the blood, with slight more prominent effect of rosuvastatin.Conclusion. The data makes it to conclude the simvastatin, atorvastatin and rosuvastatin are equally effective hypolipidemic drugs in HL type IIA and IIB patients. The time frame, type and grade of positive changes in lipid profile are almost the same, and in rosuvastatin just slightly more prominent.https://cardiovascular.elpub.ru/jour/article/view/791statinshyperlipidemia |
| spellingShingle | A. S. Sivkov E. V. Shih M. A. Osadchuk S. K. Sivkova N. V. Kireeva N. P. Chernus COMPLEX ASSESSMENT OF EFFICACY OF STATINS PRESCRIBED AT MOST BY CLINICIANS Кардиоваскулярная терапия и профилактика statins hyperlipidemia |
| title | COMPLEX ASSESSMENT OF EFFICACY OF STATINS PRESCRIBED AT MOST BY CLINICIANS |
| title_full | COMPLEX ASSESSMENT OF EFFICACY OF STATINS PRESCRIBED AT MOST BY CLINICIANS |
| title_fullStr | COMPLEX ASSESSMENT OF EFFICACY OF STATINS PRESCRIBED AT MOST BY CLINICIANS |
| title_full_unstemmed | COMPLEX ASSESSMENT OF EFFICACY OF STATINS PRESCRIBED AT MOST BY CLINICIANS |
| title_short | COMPLEX ASSESSMENT OF EFFICACY OF STATINS PRESCRIBED AT MOST BY CLINICIANS |
| title_sort | complex assessment of efficacy of statins prescribed at most by clinicians |
| topic | statins hyperlipidemia |
| url | https://cardiovascular.elpub.ru/jour/article/view/791 |
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